# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4529074 | 34 | Drug metabolism | 0 | ALA4339685 | Metabolite_Detected | ||||||
2. | ALA4529074 | 34 | Drug metabolism | 0 | ALA4339684 | Metabolite_Detected | ||||||
3. | ALA4529074 | 34 | Drug metabolism | 0 | ALA4339683 | Metabolite_Detected | ||||||
4. | ALA4529074 | 34 | Tmax | = | 0.5 | hr | ALA4339676 | hr | ||||
5. | ALA4529074 | 34 | Cmax | = | 802 | ng/mg | ALA4339678 | ng/mg | ||||
6. | ALA4529074 | 34 | Occ | = | 41 | % | ALA4339675 | % | Rattus norvegicus | |||
7. | ALA4529074 | 34 | Occ | = | 96 | % | ALA4339674 | % | Rattus norvegicus | |||
8. | ALA4529074 | 34 | Occ | = | 80 | % | ALA4339673 | % | Rattus norvegicus | |||
9. | ALA4529074 | 34 | CLH | = | 70 | ml/min.kg | ALA4339672 | mL.min-1.kg-1 | ||||
10. | ALA4529074 | 34 | Tmax | = | 0.3 | hr | ALA4339671 | hr | ||||
11. | ALA4529074 | 34 | AUC | = | 226 | hr.ng/ml | ALA4339670 | ng.hr.mL-1 | ||||
12. | ALA4529074 | 34 | Cmax | = | 184 | ng/ml | ALA4339669 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
13. | ALA4529074 | 34 | Vdss | = | 1.4 | L/Kg | ALA4339668 | L.kg-1 | ||||
14. | ALA4529074 | 34 | CL | = | 90 | ml/min.kg | ALA4339667 | mL.min-1.kg-1 | ||||
15. | ALA4529074 | 34 | Ratio | = | 3.5 | ALA4339666 | ||||||
16. | ALA4529074 | 34 | IC50 | > | 10 | uM | ALA4339665 | nM | Homo sapiens | |||
17. | ALA4529074 | 34 | ERH | = | 0.74 | ALA4339664 | ||||||
18. | ALA4529074 | 34 | IC50 | = | 8.4 | uM | ALA4339659 | 5.08 | nM | Homo sapiens | ||
19. | ALA4529074 | 34 | ERH | = | 0.82 | ALA4339657 | ||||||
20. | ALA4529074 | 34 | Ki | = | 4.3 | nM | ALA4339656 | 8.37 | nM | Rattus norvegicus |