| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4530642 | 63; TUG-2015 | INH | 0 | ALA4404882 | Not Active | % | Homo sapiens | ||||
| 2. | ALA4530642 | 63; TUG-2015 | Activity | 0 | ALA4404881 | Not Active | Homo sapiens | |||||
| 3. | ALA4530642 | 63; TUG-2015 | Activity | 0 | ALA4404880 | Not Active | Homo sapiens | |||||
| 4. | ALA4530642 | 63; TUG-2015 | Activity | 0 | ALA4404879 | Not Active | Homo sapiens | |||||
| 5. | ALA4530642 | 63; TUG-2015 | Activity | 0 | ALA4404878 | Not Active | Homo sapiens | |||||
| 6. | ALA4530642 | 63; TUG-2015 | pEC50 | = | 5.96 | ALA4404877 | 5.96 | nM | Mus musculus | |||
| 7. | ALA4530642 | 63; TUG-2015 | pEC50 | = | 6.39 | ALA4404876 | 6.39 | nM | Rattus norvegicus | |||
| 8. | ALA4530642 | 63; TUG-2015 | F | = | 66 | % | ALA4404875 | % | ||||
| 9. | ALA4530642 | 63; TUG-2015 | AUC | = | 325000 | ng.min/ml | ALA4404874 | ng.hr.mL-1 | ||||
| 10. | ALA4530642 | 63; TUG-2015 | Cmax | = | 3800 | ng/ml | ALA4404873 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 11. | ALA4530642 | 63; TUG-2015 | Tmax | = | 15 | min | ALA4404872 | hr | ||||
| 12. | ALA4530642 | 63; TUG-2015 | t1/2 | = | 51.8 | min | ALA4404871 | hr | ||||
| 13. | ALA4530642 | 63; TUG-2015 | CL | = | 20.3 | ml/min.kg | ALA4404870 | mL.min-1.kg-1 | ||||
| 14. | ALA4530642 | 63; TUG-2015 | Vd | = | 1110 | ml/kg | ALA4404869 | L.kg-1 | ||||
| 15. | ALA4530642 | 63; TUG-2015 | t1/2 | = | 37.8 | min | ALA4404868 | hr | ||||
| 16. | ALA4530642 | 63; TUG-2015 | Stability | = | 41 | % | ALA4404867 | % | ||||
| 17. | ALA4530642 | 63; TUG-2015 | logD | > | 4.3 | ALA4404866 | ||||||
| 18. | ALA4530642 | 63; TUG-2015 | Kinetic_solubility | = | 9 | uM | ALA4404865 | nM | ||||
| 19. | ALA4530642 | 63; TUG-2015 | Emax | = | 99 | % | ALA4404863 | % | Homo sapiens | |||
| 20. | ALA4530642 | 63; TUG-2015 | pEC50 | = | 6.79 | ALA4404862 | 6.79 | nM | Homo sapiens |
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