| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4531460 | 40 | Activity | = | 217 | % | ALA4411253 | % | Rattus norvegicus | |||
| 2. | ALA4531460 | 40 | Activity | = | 25 | % | ALA4411252 | % | Rattus norvegicus | |||
| 3. | ALA4531460 | 40 | Drug uptake(free) | = | 493 | nM | ALA4411251 | nM | ||||
| 4. | ALA4531460 | 40 | Cp(f) | = | 1890 | nM | ALA4411250 | nM | ||||
| 5. | ALA4531460 | 40 | BPR | = | 0.53 | ALA4411249 | ||||||
| 6. | ALA4531460 | 40 | Drug uptake | = | 355 | nM | ALA4411248 | nM | ||||
| 7. | ALA4531460 | 40 | Drug uptake | = | 1912 | nM | ALA4411247 | nM | ||||
| 8. | ALA4531460 | 40 | Cp | = | 3579 | nM | ALA4411246 | nM | ||||
| 9. | ALA4531460 | 40 | IC50 | > | 5 | uM | ALA4411244 | nM | Homo sapiens | |||
| 10. | ALA4531460 | 40 | Ratio | = | 31 | ALA4411242 | ||||||
| 11. | ALA4531460 | 40 | K(p,uu,brain) | = | 0.26 | ALA4411241 | ||||||
| 12. | ALA4531460 | 40 | Fu | = | 25.8 | % | ALA4411234 | |||||
| 13. | ALA4531460 | 40 | Fu | = | 52.8 | % | ALA4411233 | |||||
| 14. | ALA4531460 | 40 | CL | = | 87 | ml/min.kg | ALA4411232 | mL.min-1.kg-1 | ||||
| 15. | ALA4531460 | 40 | t1/2 | = | 0.8 | hr | ALA4411231 | hr | ||||
| 16. | ALA4531460 | 40 | F | = | 64 | % | ALA4411230 | % | ||||
| 17. | ALA4531460 | 40 | Ratio | = | 1.1 | ALA4411229 | ||||||
| 18. | ALA4531460 | 40 | Papp | = | 25.1 | 10'-6 cm/s | ALA4411228 | 10'-6 cm/s | ||||
| 19. | ALA4531460 | 40 | Stability | = | 11 | uL/min | ALA4411227 | uL/min | ||||
| 20. | ALA4531460 | 40 | Kinetic_solubility | = | 115 | ug ml-1 | ALA4411226 | ug.mL-1 |
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