# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4531750 | 30 | IC50 | > | 10 | uM | ALA4728777 | nM | Homo sapiens | |||
2. | ALA4531750 | 30 | Drug metabolism | 0 | ALA4339685 | Metabolite_Detected | ||||||
3. | ALA4531750 | 30 | Drug metabolism | 0 | ALA4339684 | Metabolite_Detected | ||||||
4. | ALA4531750 | 30 | Drug metabolism | 0 | ALA4339683 | Metabolite_Detected | ||||||
5. | ALA4531750 | 30 | PB | = | 98.27 | % | ALA4339677 | % | ||||
6. | ALA4531750 | 30 | Tmax | = | 0.5 | hr | ALA4339676 | hr | ||||
7. | ALA4531750 | 30 | Cmax | = | 1972 | ng/mg | ALA4339678 | ng/mg | ||||
8. | ALA4531750 | 30 | Occ | = | 76 | % | ALA4339675 | % | Rattus norvegicus | |||
9. | ALA4531750 | 30 | Occ | = | 84 | % | ALA4339674 | % | Rattus norvegicus | |||
10. | ALA4531750 | 30 | Occ | = | 77 | % | ALA4339673 | % | Rattus norvegicus | |||
11. | ALA4531750 | 30 | Tmax | = | 0.67 | hr | ALA4339671 | hr | ||||
12. | ALA4531750 | 30 | AUC | = | 4728 | hr.ng/ml | ALA4339670 | ng.hr.mL-1 | ||||
13. | ALA4531750 | 30 | Cmax | = | 2330 | ng/ml | ALA4339669 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
14. | ALA4531750 | 30 | Vdss | = | 0.5 | L/Kg | ALA4339668 | L.kg-1 | ||||
15. | ALA4531750 | 30 | CL | = | 25 | ml/min.kg | ALA4339667 | mL.min-1.kg-1 | ||||
16. | ALA4531750 | 30 | Ratio | = | 3.5 | ALA4339666 | ||||||
17. | ALA4531750 | 30 | IC50 | > | 10 | uM | ALA4339665 | nM | Homo sapiens | |||
18. | ALA4531750 | 30 | ERH | = | 0.48 | ALA4339664 | ||||||
19. | ALA4531750 | 30 | IC50 | > | 10 | uM | ALA4339663 | nM | Homo sapiens | |||
20. | ALA4531750 | 30 | IC50 | > | 10 | uM | ALA4339662 | nM | Homo sapiens |