| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4532318 | 3f; ARN24139 | Cp | = | 400 | ng/ml | ALA4345380 | ng/ml | ||||
| 2. | ALA4532318 | 3f; ARN24139 | Cp | = | 400 | ng/ml | ALA4345379 | ng/ml | ||||
| 3. | ALA4532318 | 3f; ARN24139 | Cp | = | 551 | ng/ml | ALA4345378 | ng/ml | ||||
| 4. | ALA4532318 | 3f; ARN24139 | F | = | 8 | % | ALA4345377 | % | ||||
| 5. | ALA4532318 | 3f; ARN24139 | Vd | = | 18 | L/Kg | ALA4345376 | L.kg-1 | ||||
| 6. | ALA4532318 | 3f; ARN24139 | beta t1/2 | = | 190 | min | ALA4345375 | hr | ||||
| 7. | ALA4532318 | 3f; ARN24139 | AUC | = | 77385 | min.ng/ml | ALA4345374 | ng.hr.mL-1 | ||||
| 8. | ALA4532318 | 3f; ARN24139 | Tmax | = | 120 | min | ALA4345373 | hr | ||||
| 9. | ALA4532318 | 3f; ARN24139 | Cmax | = | 428 | ng/ml | ALA4345372 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 10. | ALA4532318 | 3f; ARN24139 | CL | = | 0.004 | L/min/kg | ALA4345371 | mL.min-1.kg-1 | ||||
| 11. | ALA4532318 | 3f; ARN24139 | Vd | = | 3 | L/Kg | ALA4345370 | L.kg-1 | ||||
| 12. | ALA4532318 | 3f; ARN24139 | beta t1/2 | = | 30 | min | ALA4345369 | hr | ||||
| 13. | ALA4532318 | 3f; ARN24139 | AUC | = | 295528 | min.ng/ml | ALA4345368 | ng.hr.mL-1 | ||||
| 14. | ALA4532318 | 3f; ARN24139 | Tmax | = | 5 | min | ALA4345367 | hr | ||||
| 15. | ALA4532318 | 3f; ARN24139 | Cmax | = | 7366 | ng/ml | ALA4345366 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 16. | ALA4532318 | 3f; ARN24139 | PPB | > | 99 | % | ALA4345365 | % | ||||
| 17. | ALA4532318 | 3f; ARN24139 | PPB | > | 99 | % | ALA4345364 | % | ||||
| 18. | ALA4532318 | 3f; ARN24139 | Therm_solubility | = | 30 | uM | ALA4345363 | nM | ||||
| 19. | ALA4532318 | 3f; ARN24139 | t1/2 | > | 60 | min | ALA4345362 | hr | ||||
| 20. | ALA4532318 | 3f; ARN24139 | t1/2 | > | 120 | min | ALA4345361 | hr |
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