# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4532724 | 8 | F | = | 35 | % | ALA4481405 | % | ||||
2. | ALA4532724 | 8 | AUClast | = | 1.54 | hr.microg/ml | ALA4481404 | ng.hr.mL-1 | ||||
3. | ALA4532724 | 8 | Cmax | = | 0.673 | ug ml-1 | ALA4481403 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
4. | ALA4532724 | 8 | AUClast | = | 2.18 | hr.microg/ml | ALA4481402 | ng.hr.mL-1 | ||||
5. | ALA4532724 | 8 | Vdss | = | 2716 | ml/kg | ALA4481401 | L.kg-1 | ||||
6. | ALA4532724 | 8 | CL | = | 2296 | ml/hr/kg | ALA4481400 | mL.min-1.kg-1 | ||||
7. | ALA4532724 | 8 | Cmax | = | 4.13 | ug ml-1 | ALA4481399 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
8. | ALA4532724 | 8 | Papp | = | 15.1 | 10'-6 cm/s | ALA4481398 | 10'-6 cm/s | ||||
9. | ALA4532724 | 8 | Fu | = | 0.003 | ALA4481396 | ||||||
10. | ALA4532724 | 8 | CLH | = | 145 | microL/min/mg | ALA4481395 | mL.min-1.g-1 | ||||
11. | ALA4532724 | 8 | EC50 | = | 1.3 | nM | ALA4481394 | 8.89 | nM | Wolbachia | ||
12. | ALA4532724 | 8 | EC50 | = | 6.3 | nM | ALA4481393 | 8.20 | nM | Wolbachia |