# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | FGFR1/DDR2 inhibitor 1 | 11k | TGI | 0 | ALA4412449 | Dose-dependent effect | Homo sapiens | |||||
2. | FGFR1/DDR2 inhibitor 1 | 11k | IC50 | = | 93 | nM | ALA4412431 | 7.03 | nM | Homo sapiens | ||
3. | FGFR1/DDR2 inhibitor 1 | 11k | IC50 | = | 306.6 | nM | ALA4412430 | 6.51 | nM | |||
4. | FGFR1/DDR2 inhibitor 1 | 11k | IC50 | = | 31.8 | nM | ALA4412429 | 7.50 | nM | Homo sapiens | ||
5. | FGFR1/DDR2 inhibitor 1 | 11k | IC50 | = | 93.4 | nM | ALA4412428 | 7.03 | nM | Homo sapiens | ||
6. | FGFR1/DDR2 inhibitor 1 | 11k | IC50 | = | 108.4 | nM | ALA4412427 | 6.96 | nM | Homo sapiens | ||
7. | FGFR1/DDR2 inhibitor 1 | 11k | t1/2 | = | 3.05 | hr | ALA4412323 | hr | ||||
8. | FGFR1/DDR2 inhibitor 1 | 11k | CLH | = | 0 | uL/min | ALA4412454 | uL/min | ||||
9. | FGFR1/DDR2 inhibitor 1 | 11k | CLH | = | 0 | uL/min | ALA4412453 | uL/min | ||||
10. | FGFR1/DDR2 inhibitor 1 | 11k | IC50 | > | 40 | uM | ALA4412447 | nM | Homo sapiens | |||
11. | FGFR1/DDR2 inhibitor 1 | 11k | INH | = | 90 | % | ALA4412446 | % | Homo sapiens | |||
12. | FGFR1/DDR2 inhibitor 1 | 11k | INH | = | 110 | % | ALA4412445 | % | Homo sapiens | |||
13. | FGFR1/DDR2 inhibitor 1 | 11k | INH | = | 100 | % | ALA4412444 | % | Homo sapiens | |||
14. | FGFR1/DDR2 inhibitor 1 | 11k | INH | = | 70 | % | ALA4412443 | % | Homo sapiens | |||
15. | FGFR1/DDR2 inhibitor 1 | 11k | INH | = | 100 | % | ALA4412442 | % | Homo sapiens | |||
16. | FGFR1/DDR2 inhibitor 1 | 11k | INH | = | 90 | % | ALA4412441 | % | Homo sapiens | |||
17. | FGFR1/DDR2 inhibitor 1 | 11k | INH | = | 64 | % | ALA4412440 | % | Homo sapiens | |||
18. | FGFR1/DDR2 inhibitor 1 | 11k | INH | = | 20 | % | ALA4412439 | % | Homo sapiens | |||
19. | FGFR1/DDR2 inhibitor 1 | 11k | INH | = | 83 | % | ALA4412438 | % | Homo sapiens | |||
20. | FGFR1/DDR2 inhibitor 1 | 11k | INH | = | 10 | % | ALA4412437 | % | Homo sapiens |