| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4535197 | 14 | AUC | = | 11600 | nM.hr | ALA4394752 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 2. | ALA4535197 | 14 | beta t1/2 | = | 2.5 | hr | ALA4394750 | hr | ||||
| 3. | ALA4535197 | 14 | Vdss | = | 0.1 | L/Kg | ALA4394749 | L.kg-1 | ||||
| 4. | ALA4535197 | 14 | AUC | = | 48700 | nM.hr | ALA4394748 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 5. | ALA4535197 | 14 | Cmax | = | 26000 | nM | ALA4394747 | nM | ||||
| 6. | ALA4535197 | 14 | F | = | 25 | % | ALA4394738 | % | ||||
| 7. | ALA4535197 | 14 | CL | = | 0.7 | ml/min.Kg | ALA4394735 | mL.min-1.kg-1 | ||||
| 8. | ALA4535197 | 14 | Ratio IC50 | > | 200 | ALA4394739 | ||||||
| 9. | ALA4535197 | 14 | Ratio IC50 | > | 200 | ALA4394740 | ||||||
| 10. | ALA4535197 | 14 | IC50 | = | 3.3 | uM | ALA4394744 | 5.48 | nM | Homo sapiens | ||
| 11. | ALA4535197 | 14 | IC50 | = | 4 | uM | ALA4394743 | 5.40 | nM | Homo sapiens | ||
| 12. | ALA4535197 | 14 | logPapp | = | -5 | ALA4394742 | ||||||
| 13. | ALA4535197 | 14 | IC50 | = | 0.16 | uM | ALA4394741 | 6.80 | nM | Homo sapiens | ||
| 14. | ALA4535197 | 14 | IC50 | = | 0.003 | uM | ALA4394736 | 8.52 | nM | Homo sapiens |
The page will load shortly, Thanks for your patience!