| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4535824 | 15 | Drug metabolism | 0 | ALA4481441 | Metabolite_Detected | ||||||
| 2. | ALA4535824 | 15 | Activity | 0 | ALA4481440 | Non-Toxic | ||||||
| 3. | ALA4535824 | 15 | Activity | = | 99.7 | % | ALA4481437 | % | Litomosoides sigmodontis | |||
| 4. | ALA4535824 | 15 | Activity | = | 99.2 | % | ALA4481436 | % | Litomosoides sigmodontis | |||
| 5. | ALA4535824 | 15 | Activity | = | 13.4 | % | ALA4481435 | % | Brugia malayi | |||
| 6. | ALA4535824 | 15 | Activity | = | 16.6 | % | ALA4481434 | % | Brugia malayi | |||
| 7. | ALA4535824 | 15 | Activity | = | 45.5 | % | ALA4481433 | % | Brugia malayi | |||
| 8. | ALA4535824 | 15 | Activity | 0 | ALA4481432 | Non-Toxic | ||||||
| 9. | ALA4535824 | 15 | INH | < | 10 | % | ALA4481431 | % | Homo sapiens | |||
| 10. | ALA4535824 | 15 | Activity | = | 98.8 | % | ALA4481430 | % | Brugia malayi | |||
| 11. | ALA4535824 | 15 | Activity | = | 75.4 | % | ALA4481429 | % | Brugia malayi | |||
| 12. | ALA4535824 | 15 | AUClast | = | 23 | hr.microg/ml | ALA4481426 | ng.hr.mL-1 | ||||
| 13. | ALA4535824 | 15 | Tmax | = | 0.5 | hr | ALA4481425 | hr | ||||
| 14. | ALA4535824 | 15 | Cmax | = | 6.38 | ug ml-1 | ALA4481424 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 15. | ALA4535824 | 15 | beta t1/2 | = | 4.6 | hr | ALA4481423 | hr | ||||
| 16. | ALA4535824 | 15 | AUC | = | 24.2 | hr.microg/ml | ALA4481422 | ng.hr.mL-1 | ||||
| 17. | ALA4535824 | 15 | AUClast | = | 23.7 | hr.microg/ml | ALA4481421 | ng.hr.mL-1 | ||||
| 18. | ALA4535824 | 15 | Tmax | = | 0.25 | hr | ALA4481420 | hr | ||||
| 19. | ALA4535824 | 15 | Cmax | = | 4.25 | ug ml-1 | ALA4481419 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 20. | ALA4535824 | 15 | beta t1/2 | = | 7.51 | hr | ALA4481418 | hr |
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