# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4535889 | 22d | F | = | 3.1 | % | ALA4412512 | % | ||||
2. | ALA4535889 | 22d | t1/2 | = | 2.4 | hr | ALA4412511 | hr | ||||
3. | ALA4535889 | 22d | Cmax | = | 231 | ng/ml | ALA4412510 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
4. | ALA4535889 | 22d | AUC | = | 360 | ng.hr/ml | ALA4412509 | ng.hr.mL-1 | ||||
5. | ALA4535889 | 22d | Stability | = | 88 | % | ALA4412504 | % | ||||
6. | ALA4535889 | 22d | Stability | = | 100 | % | ALA4412503 | % | ||||
7. | ALA4535889 | 22d | Stability | = | 37 | % | ALA4412502 | % | ||||
8. | ALA4535889 | 22d | Stability | = | 33 | % | ALA4412501 | % | ||||
9. | ALA4535889 | 22d | IC50 | = | 169 | nM | ALA4412497 | 6.77 | nM | Homo sapiens | ||
10. | ALA4535889 | 22d | IC50 | = | 41 | nM | ALA4412490 | 7.39 | nM | Homo sapiens | ||
11. | ALA4535889 | 22d | INH | = | 49 | % | ALA4412495 | % | Homo sapiens | |||
12. | ALA4535889 | 22d | INH | = | 97 | % | ALA4412494 | % | Homo sapiens |