# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4536241 | 33 | Activity | 0 | ALA4431866 | Non-Toxic | ||||||
2. | ALA4536241 | 33 | Activity | 0 | ALA4431836 | Toxic | ||||||
3. | ALA4536241 | 33 | Activity | 0 | ALA4431835 | Toxic | ||||||
4. | ALA4536241 | 33 | t1/2 | = | 51 | hr | ALA4431834 | hr | ||||
5. | ALA4536241 | 33 | Vd/F | = | 2.3 | L/Kg | ALA4431832 | L.kg-1 | ||||
6. | ALA4536241 | 33 | CL/F | = | 30 | ml/hr/kg | ALA4431831 | mL.min-1.kg-1 | ||||
7. | ALA4536241 | 33 | AUC | = | 849 | hr.umol/L | ALA4431829 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
8. | ALA4536241 | 33 | Cmax | = | 9.8 | uM | ALA4431826 | nM | ||||
9. | ALA4536241 | 33 | Tmax | = | 24 | hr | ALA4431824 | hr | ||||
10. | ALA4536241 | 33 | Ratio IC50 | > | 5000 | ALA4431821 | ||||||
11. | ALA4536241 | 33 | IC50 | = | 0.28 | uM | ALA4431820 | 6.55 | nM | Homo sapiens | ||
12. | ALA4536241 | 33 | Ratio IC50 | = | 140 | ALA4431818 | ||||||
13. | ALA4536241 | 33 | EC50 | > | 25 | uM | ALA4431817 | nM | ||||
14. | ALA4536241 | 33 | EC50 | = | 0.47 | uM | ALA4431816 | 6.33 | nM | Toxoplasma gondii | ||
15. | ALA4536241 | 33 | BPR | = | 1.65 | ALA4431815 | ||||||
16. | ALA4536241 | 33 | Cp | = | 1.23 | uM | ALA4431814 | uM | ||||
17. | ALA4536241 | 33 | Drug uptake | = | 1.9 | uM | ALA4431813 | uM | ||||
18. | ALA4536241 | 33 | Drugabsorption | 0 | ALA4431811 | Active | ||||||
19. | ALA4536241 | 33 | t1/2 | = | 13 | hr | ALA4431809 | hr | ||||
20. | ALA4536241 | 33 | Vdss | = | 5.8 | L/Kg | ALA4431808 | L.kg-1 |