Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Assay	Assay Organism
1.	ALA4536433	12; GNF-Pf-3587	Vz	=	7.3	L/Kg	ALA4392043		L.kg-1
2.	ALA4536433	12; GNF-Pf-3587	CL(app)	=	52	ml/min.kg	ALA4392041		mL.min-1.kg-1
3.	ALA4536433	12; GNF-Pf-3587	t1/2	=	1.7	hr	ALA4392039		hr
4.	ALA4536433	12; GNF-Pf-3587	CLH	=	1.4	microL/min/mg	ALA4392038		mL.min-1.g-1
5.	ALA4536433	12; GNF-Pf-3587	Ratio IC50	=	19		ALA4392037
6.	ALA4536433	12; GNF-Pf-3587	IC50	=	8950	nM	ALA4392036	5.05	nM	Homo sapiens
7.	ALA4536433	12; GNF-Pf-3587	IC50	>	10000	nM	ALA4392032		nM	Plasmodium falciparum
8.	ALA4536433	12; GNF-Pf-3587	IC50	>	10000	nM	ALA4392031		nM	Plasmodium falciparum
9.	ALA4536433	12; GNF-Pf-3587	IC50	>	10000	nM	ALA4392030		nM	Homo sapiens
10.	ALA4536433	12; GNF-Pf-3587	t1/2	=	161	min	ALA4392027		hr
11.	ALA4536433	12; GNF-Pf-3587	IC50	=	460	nM	ALA4392025	6.34	nM	Plasmodium falciparum