| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4537107 | 8r | Ratio | = | 2.3 | ALA4346906 | ||||||
| 2. | ALA4537107 | 8r | Ratio | = | 2.5 | ALA4346905 | Rattus norvegicus | |||||
| 3. | ALA4537107 | 8r | IC50 | = | 7.32 | uM | ALA4346904 | 5.13 | nM | Homo sapiens | ||
| 4. | ALA4537107 | 8r | Cmax | = | 43.5 | ng/ml | ALA4346903 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 5. | ALA4537107 | 8r | Tmax | = | 7 | hr | ALA4346902 | hr | ||||
| 6. | ALA4537107 | 8r | MRT | = | 8.53 | hr | ALA4346901 | hr | ||||
| 7. | ALA4537107 | 8r | t1/2 | = | 3.2 | hr | ALA4346900 | hr | ||||
| 8. | ALA4537107 | 8r | CL | = | 71190 | ml/hr.kg | ALA4346899 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 9. | ALA4537107 | 8r | AUCt | = | 228 | hr.ng/ml | ALA4346898 | ng.hr.mL-1 | ||||
| 10. | ALA4537107 | 8r | AUC | = | 281 | hr.ng/ml | ALA4346897 | ng.hr.mL-1 | ||||
| 11. | ALA4537107 | 8r | Selectivity ratio | = | 8 | ALA4346896 | Moraxella catarrhalis | |||||
| 12. | ALA4537107 | 8r | MBC | = | 32 | ug ml-1 | ALA4346895 | ug ml-1 | Moraxella catarrhalis | |||
| 13. | ALA4537107 | 8r | MIC | = | 4 | ug ml-1 | ALA4346894 | ug.mL-1 | Moraxella catarrhalis | |||
| 14. | ALA4537107 | 8r | Selectivity ratio | = | 4 | ALA4346893 | Streptococcus pyogenes | |||||
| 15. | ALA4537107 | 8r | MBC | = | 0.5 | ug ml-1 | ALA4346892 | ug ml-1 | Streptococcus pyogenes | |||
| 16. | ALA4537107 | 8r | MIC | = | 0.125 | ug ml-1 | ALA4346891 | ug.mL-1 | Streptococcus pyogenes | |||
| 17. | ALA4537107 | 8r | Selectivity ratio | > | 8 | ALA4346890 | Streptococcus pyogenes | |||||
| 18. | ALA4537107 | 8r | MBC | > | 1 | ug ml-1 | ALA4346889 | ug ml-1 | Streptococcus pyogenes | |||
| 19. | ALA4537107 | 8r | MIC | = | 0.125 | ug ml-1 | ALA4346888 | ug.mL-1 | Streptococcus pyogenes | |||
| 20. | ALA4537107 | 8r | MBC | > | 256 | ug ml-1 | ALA4346886 | ug ml-1 | Staphylococcus aureus |
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