# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4537625 | 24 | F | = | 72 | % | ALA4481585 | % | ||||
2. | ALA4537625 | 24 | MRT | = | 4.9 | hr | ALA4481584 | hr | ||||
3. | ALA4537625 | 24 | AUC | = | 15 | uM.hr | ALA4481583 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
4. | ALA4537625 | 24 | Vdss | = | 0.76 | L/Kg | ALA4481582 | L.kg-1 | ||||
5. | ALA4537625 | 24 | CL | = | 0.25 | L/hr/kg | ALA4481581 | mL.min-1.kg-1 | ||||
6. | ALA4537625 | 24 | beta t1/2 | = | 4.2 | hr | ALA4481580 | hr | ||||
7. | ALA4537625 | 24 | IC50 | > | 50 | uM | ALA4481579 | nM | Homo sapiens | |||
8. | ALA4537625 | 24 | IC50 | > | 50 | uM | ALA4481578 | nM | Homo sapiens | |||
9. | ALA4537625 | 24 | IC50 | > | 50 | uM | ALA4481577 | nM | Homo sapiens | |||
10. | ALA4537625 | 24 | IC50 | > | 50 | uM | ALA4481576 | nM | Homo sapiens | |||
11. | ALA4537625 | 24 | IC50 | > | 50 | uM | ALA4481575 | nM | Homo sapiens | |||
12. | ALA4537625 | 24 | IC50 | > | 50 | uM | ALA4481574 | nM | Homo sapiens | |||
13. | ALA4537625 | 24 | EC50 | > | 20 | uM | ALA4481573 | nM | Homo sapiens | |||
14. | ALA4537625 | 24 | EC50 | > | 20 | uM | ALA4481572 | nM | Homo sapiens | |||
15. | ALA4537625 | 24 | EC50 | > | 20 | uM | ALA4481571 | nM | Homo sapiens | |||
16. | ALA4537625 | 24 | EC50 | > | 20 | uM | ALA4481570 | nM | ||||
17. | ALA4537625 | 24 | EC50 | > | 20 | uM | ALA4481569 | nM | Homo sapiens | |||
18. | ALA4537625 | 24 | Activity | 0 | ALA4481568 | Active | Mus musculus | |||||
19. | ALA4537625 | 24 | ED50 | = | 3 | mg kg-1 | ALA4481567 | mg.kg-1 | Mus musculus | |||
20. | ALA4537625 | 24 | Activity | 0 | ALA4481567 | Dose-dependent effect | Mus musculus |