# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4539370 | 19 | Activity | 0 | ALA4397524 | Not Active | Rattus norvegicus | |||||
2. | ALA4539370 | 19 | t1/2 | = | 12 | min | ALA4397523 | hr | ||||
3. | ALA4539370 | 19 | Activity | = | 80 | % | ALA4397521 | % | Rattus norvegicus | |||
4. | ALA4539370 | 19 | Ratio EC50 | = | 10 | ALA4397520 | ||||||
5. | ALA4539370 | 19 | Activity | = | 1 | g | ALA4397519 | g | Rattus norvegicus | |||
6. | ALA4539370 | 19 | Activity | = | 5 | g | ALA4397517 | g | Rattus norvegicus | |||
7. | ALA4539370 | 19 | EC50 | = | 0.43 | pM | ALA4397516 | nM | Rattus norvegicus | |||
8. | ALA4539370 | 19 | Activity | 0 | ALA4397515 | Dose-dependent effect | Rattus norvegicus | |||||
9. | ALA4539370 | 19 | beta t1/2 | = | 6.4 | min | ALA4397514 | hr | ||||
10. | ALA4539370 | 19 | Efficacy | = | 91 | % | ALA4397513 | % | Rattus norvegicus | |||
11. | ALA4539370 | 19 | EC50 | = | 0.05 | nM | ALA4397512 | 10.30 | nM | Rattus norvegicus | ||
12. | ALA4539370 | 19 | Activity | 0 | ALA4397511 | Not Active | Homo sapiens | |||||
13. | ALA4539370 | 19 | PPB | = | 92 | % | ALA4397510 | % | ||||
14. | ALA4539370 | 19 | CL | = | 60 | % | ALA4397509 | % | ||||
15. | ALA4539370 | 19 | CL | = | 42 | ml/min.Kg | ALA4397508 | mL.min-1.kg-1 | ||||
16. | ALA4539370 | 19 | Activity | 0 | ALA4397507 | Not Active | Homo sapiens | |||||
17. | ALA4539370 | 19 | Ratio EC50 | = | 2100 | ALA4397506 | ||||||
18. | ALA4539370 | 19 | EC50 | = | 530 | nM | ALA4397503 | 6.28 | nM | Homo sapiens | ||
19. | ALA4539370 | 19 | EC50 | = | 0.25 | nM | ALA4397500 | 9.60 | nM | Homo sapiens |