Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4539535	24a	Kinetic_solubility	=	17	uM	ALA4384260			nM
2.	ALA4539535	24a	Kinetic_solubility	=	27	uM	ALA4384259			nM
3.	ALA4539535	24a	IC50	=	0.22	uM	ALA4384236	6.66		nM	Trypanosoma brucei brucei
4.	ALA4539535	24a	pIC50	=	6.7		ALA4384236	6.70		nM	Trypanosoma brucei brucei
5.	ALA4539535	24a	MIC	>	32	ug ml-1	ALA4384233			ug.mL-1	Mycobacterium tuberculosis
6.	ALA4539535	24a	MIC=<90	>	32	ug ml-1	ALA4384231			ug ml-1	Mycobacterium tuberculosis
7.	ALA4539535	24a	pIC50	<	4.6		ALA4384229			nM	Entamoeba histolytica
8.	ALA4539535	24a	IC50	>	25	uM	ALA4384229			nM	Entamoeba histolytica
9.	ALA4539535	24a	IC50	=	10	uM	ALA4384228	5.00		nM	Giardia intestinalis
10.	ALA4539535	24a	pIC50	=	5		ALA4384228	5.00		nM	Giardia intestinalis
11.	ALA4539535	24a	t1/2	=	1.2	hr	ALA5106676			hr
12.	ALA4539535	24a	CL	=	3.38	ml/min.kg	ALA5106675			mL.min-1.kg-1
13.	ALA4539535	24a	Vdss	=	0.34	L/Kg	ALA5106674			L.kg-1
14.	ALA4539535	24a	F	=	87	%	ALA5106673			%
15.	ALA4539535	24a	t1/2	=	3.2	hr	ALA5106672			hr
16.	ALA4539535	24a	Tmax	=	2	hr	ALA5106671			hr
17.	ALA4539535	24a	AUC	=	88.3	microg.hr/mL	ALA5106670			ng.hr.mL-1
18.	ALA4539535	24a	Cmax	=	13	ug ml-1	ALA5106669		standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM
19.	ALA4539535	24a	Stability		0		ALA5106660		ND	%
20.	ALA4539535	24a	Stability		0		ALA5106659		ND	%