# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4539946 | 24 | Ratio | = | 4 | ALA4325070 | ||||||
2. | ALA4539946 | 24 | Activity | 0 | ALA4325069 | Not Active | ||||||
3. | ALA4539946 | 24 | fAUC | = | 4.73 | ug.hr/ml | ALA4325041 | ng.hr.mL-1 | ||||
4. | ALA4539946 | 24 | AUC | = | 47.3 | ug.hr/ml | ALA4325039 | ng.hr.mL-1 | ||||
5. | ALA4539946 | 24 | PPB | = | 90 | % | ALA4325037 | % | ||||
6. | ALA4539946 | 24 | Activity | = | 2.2 | deltalog10CFU | ALA4325036 | deltalog10CFU | Escherichia coli | |||
7. | ALA4539946 | 24 | solubility | > | 830 | ug ml-1 | ALA4325033 | ug.mL-1 | ||||
8. | ALA4539946 | 24 | solubility | > | 830 | ug ml-1 | ALA4325032 | ug.mL-1 | ||||
9. | ALA4539946 | 24 | solubility | > | 830 | ug ml-1 | ALA4325031 | ug.mL-1 | ||||
10. | ALA4539946 | 24 | pKa | = | 7.8 | ALA4325030 | ||||||
11. | ALA4539946 | 24 | logD | = | 0.7 | ALA4325029 | ||||||
12. | ALA4539946 | 24 | deltaTm | = | 12.1 | K | ALA4325028 | K | Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) | |||
13. | ALA4539946 | 24 | deltaTm | = | 10.3 | K | ALA4325027 | K | Escherichia coli K-12 | |||
14. | ALA4539946 | 24 | MIC | = | 0.5 | ug ml-1 | ALA4325026 | ug.mL-1 | Pseudomonas aeruginosa | |||
15. | ALA4539946 | 24 | MIC | = | 1 | ug ml-1 | ALA4325025 | ug.mL-1 | Klebsiella pneumoniae | |||
16. | ALA4539946 | 24 | MIC | = | 0.5 | ug ml-1 | ALA4325024 | ug.mL-1 | Escherichia coli |