| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4540313 | (S)-25 | Activity | 0 | ALA4423332 | Not Active | Rattus norvegicus | |||||
| 2. | ALA4540313 | (S)-25 | CLH | = | 3 | uL/min | ALA4423297 | uL/min | ||||
| 3. | ALA4540313 | (S)-25 | Papp | = | 21 | 10'-6 cm/s | ALA4423296 | 10'-6 cm/s | ||||
| 4. | ALA4540313 | (S)-25 | Activity | 0 | ALA4423331 | Active | Rattus norvegicus | |||||
| 5. | ALA4540313 | (S)-25 | Activity | 0 | ALA4423326 | Not Active | Rattus norvegicus | |||||
| 6. | ALA4540313 | (S)-25 | Activity | 0 | ALA4423325 | Not Active | Rattus norvegicus | |||||
| 7. | ALA4540313 | (S)-25 | Activity | 0 | ALA4423324 | Active | Rattus norvegicus | |||||
| 8. | ALA4540313 | (S)-25 | F | = | 11 | % | ALA4423321 | % | ||||
| 9. | ALA4540313 | (S)-25 | beta t1/2 | = | 0.43 | hr | ALA4423315 | hr | ||||
| 10. | ALA4540313 | (S)-25 | CL | = | 44 | ml/min.Kg | ALA4423312 | mL.min-1.kg-1 | ||||
| 11. | ALA4540313 | (S)-25 | Vdss | = | 1.5 | L/Kg | ALA4423309 | L.kg-1 | ||||
| 12. | ALA4540313 | (S)-25 | CLH | = | 19 | uL/min | ALA4423308 | uL/min | ||||
| 13. | ALA4540313 | (S)-25 | Fu | = | 40 | % | ALA4423307 | |||||
| 14. | ALA4540313 | (S)-25 | Activity | 0 | ALA4423305 | Non-Toxic | Rattus norvegicus | |||||
| 15. | ALA4540313 | (S)-25 | Activity | = | 97 | % | ALA4423304 | % | Homo sapiens | |||
| 16. | ALA4540313 | (S)-25 | pEC50 | = | 9 | ALA4423287 | 9.00 | nM | Homo sapiens | |||
| 17. | ALA4540313 | (S)-25 | pIC50 | < | 5 | ALA4423302 | nM | Homo sapiens | ||||
| 18. | ALA4540313 | (S)-25 | INH | = | 90 | % | ALA4423301 | % | Rattus norvegicus | |||
| 19. | ALA4540313 | (S)-25 | pIC50 | = | 8 | ALA4423300 | 8.00 | nM | Rattus norvegicus | |||
| 20. | ALA4540313 | (S)-25 | INH | = | 68 | % | ALA4423299 | % | Homo sapiens |
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