| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4540849 | 14 | Activity | 0 | ALA4433278 | Dose-dependent effect | Homo sapiens | |||||
| 2. | ALA4540849 | 14 | Activity | 0 | ALA4433282 | Dose-dependent effect | Cavia porcellus | |||||
| 3. | ALA4540849 | 14 | INH | 0 | ALA4433279 | Dose-dependent effect | % | Rattus norvegicus | ||||
| 4. | ALA4540849 | 14 | INH | 0 | ALA4433307 | Active | % | Homo sapiens | ||||
| 5. | ALA4540849 | 14 | Activity | 0 | ALA4433305 | Active | Homo sapiens | |||||
| 6. | ALA4540849 | 14 | INH | 0 | ALA4433304 | Not Active | % | Homo sapiens | ||||
| 7. | ALA4540849 | 14 | Drug metabolism | 0 | ALA4433298 | Metabolite_Notdetected | ||||||
| 8. | ALA4540849 | 14 | Drug metabolism | 0 | ALA4433297 | Metabolite_Notdetected | ||||||
| 9. | ALA4540849 | 14 | Drug metabolism | 0 | ALA4433296 | Metabolite_Notdetected | ||||||
| 10. | ALA4540849 | 14 | Drug metabolism | 0 | ALA4433295 | Metabolite_Notdetected | ||||||
| 11. | ALA4540849 | 14 | Retention_time | = | 5.83 | min | ALA4433293 | min | ||||
| 12. | ALA4540849 | 14 | FC | < | 2 | ALA4433290 | ||||||
| 13. | ALA4540849 | 14 | FC | < | 2 | ALA4433289 | ||||||
| 14. | ALA4540849 | 14 | Ratio IC50 | > | 30 | ALA4433288 | Homo sapiens | |||||
| 15. | ALA4540849 | 14 | IC50 | = | 17.2 | uM | ALA4433287 | 4.76 | nM | Homo sapiens | ||
| 16. | ALA4540849 | 14 | Ki | = | 25 | nM | ALA4433277 | 7.60 | nM | Homo sapiens | ||
| 17. | ALA4540849 | 14 | IC50 | = | 4.04 | nM | ALA4433278 | 8.39 | nM | Homo sapiens | ||
| 18. | ALA4540849 | 14 | ED50 | = | 2.72 | mg kg-1 | ALA4433279 | mg.kg-1 | Rattus norvegicus | |||
| 19. | ALA4540849 | 14 | Ki | = | 19.9 | uM | ALA4433281 | 4.70 | nM | Homo sapiens | ||
| 20. | ALA4540849 | 14 | pA2 | = | 6.53 | ALA4433282 | 6.53 | nM | Cavia porcellus |
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