Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4541614	GNF6702	EC50	=	120	nM	ALA5246251	6.92		nM	Trypanosoma cruzi
2.	ALA4541614	GNF6702	EC50	=	70	nM	ALA5246250	7.16		nM	Trypanosoma brucei
3.	ALA4541614	GNF6702	EC50	=	18	nM	ALA5246249	7.75		nM	Leishmania donovani
4.	ALA4541614	GNF6702	Activity		0		ALA4385543		Non-Toxic
5.	ALA4541614	GNF6702	Activity	=	100	%	ALA4385540			%	Trypanosoma cruzi
6.	ALA4541614	GNF6702	Activity		0		ALA4385539		Not Active		Trypanosoma cruzi
7.	ALA4541614	GNF6702	Activity		0		ALA4385537		Bld		Trypanosoma cruzi
8.	ALA4541614	GNF6702	BPR	=	0.12		ALA4385531
9.	ALA4541614	GNF6702	Fu	=	12.7	%	ALA4385530
10.	ALA4541614	GNF6702	solubility	=	4.3	uM	ALA4385529			nM
11.	ALA4541614	GNF6702	solubility	=	2.2	uM	ALA4385528			nM
12.	ALA4541614	GNF6702	solubility	=	1.8	uM	ALA4385527			nM
13.	ALA4541614	GNF6702	solubility		0		ALA4385522		Insoluble
14.	ALA4541614	GNF6702	AUC	=	45923	min.micromol	ALA4385521		standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW	ng.hr.mL-1
15.	ALA4541614	GNF6702	Cmax	=	54.4	uM	ALA4385520			nM
16.	ALA4541614	GNF6702	t1/2	>	90	min	ALA4385519			hr
17.	ALA4541614	GNF6702	t1/2	>	90	min	ALA4385518			hr
18.	ALA4541614	GNF6702	EC50	>	2500	nM	ALA4385512			nM	Homo sapiens
19.	ALA4541614	GNF6702	EC50	>	2500	nM	ALA4385511			nM
20.	ALA4541614	GNF6702	EC50	=	16.6	nM	ALA4385510	7.78		nM	Trypanosoma brucei