# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4541614 | GNF6702 | CL | = | 2 | ml/min.kg | ALA4481167 | mL.min-1.kg-1 | ||||
2. | ALA4541614 | GNF6702 | F | < | 34 | % | ALA4481166 | % | ||||
3. | ALA4541614 | GNF6702 | BPR | = | 0.1 | ALA4481169 | ||||||
4. | ALA4541614 | GNF6702 | CC50 | > | 20 | uM | ALA4481164 | nM | Mus musculus | |||
5. | ALA4541614 | GNF6702 | CC50 | > | 50 | uM | ALA4481165 | nM | Mus musculus | |||
6. | ALA4541614 | GNF6702 | EC50 | = | 120 | nM | ALA4481163 | 6.92 | nM | Trypanosoma cruzi | ||
7. | ALA4541614 | GNF6702 | EC50 | = | 70 | nM | ALA4481162 | 7.16 | nM | Trypanosoma brucei | ||
8. | ALA4541614 | GNF6702 | EC50 | = | 18 | nM | ALA4481161 | 7.75 | nM | Leishmania donovani | ||
9. | ALA4541614 | GNF6702 | ERH | = | 0.3 | ALA4668886 | ||||||
10. | ALA4541614 | GNF6702 | ERH | = | 0.46 | ALA4668885 | ||||||
11. | ALA4541614 | GNF6702 | ERH | < | 0.27 | ALA4668884 | ||||||
12. | ALA4541614 | GNF6702 | ERH | < | 0.21 | ALA4668883 | ||||||
13. | ALA4541614 | GNF6702 | solubility | = | 10 | uM | ALA4668882 | nM | ||||
14. | ALA4541614 | GNF6702 | EC50 | = | 0.02 | uM | ALA4668881 | 7.70 | nM | Leishmania donovani | ||
15. | ALA4541614 | GNF6702 | IC50 | = | 0.035 | uM | ALA4668880 | 7.46 | nM | |||
16. | ALA4541614 | GNF6702 | INH | 0 | ALA4668830 | Active | % | |||||
17. | ALA4541614 | GNF6702 | Activity | 0 | ALA4385543 | Non-Toxic | ||||||
18. | ALA4541614 | GNF6702 | Activity | = | 100 | % | ALA4385540 | % | Trypanosoma cruzi | |||
19. | ALA4541614 | GNF6702 | Activity | 0 | ALA4385539 | Not Active | Trypanosoma cruzi | |||||
20. | ALA4541614 | GNF6702 | Activity | 0 | ALA4385537 | Bld | Trypanosoma cruzi |