# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4541705 | 26 | CLH | = | 500 | uL/min | ALA4478463 | uL/min | ||||
2. | ALA4541705 | 26 | CLH | < | 0.1 | uL/min | ALA4478462 | uL/min | ||||
3. | ALA4541705 | 26 | CLH | = | 51 | uL/min | ALA4478461 | uL/min | ||||
4. | ALA4541705 | 26 | CLH | = | 0.8 | uL/min | ALA4478460 | uL/min | ||||
5. | ALA4541705 | 26 | PPB | = | 70.9 | % | ALA4478459 | % | ||||
6. | ALA4541705 | 26 | PPB | = | 99.2 | % | ALA4478458 | % | ||||
7. | ALA4541705 | 26 | t1/2 | > | 24 | hr | ALA4478457 | hr | ||||
8. | ALA4541705 | 26 | t1/2 | > | 24 | hr | ALA4478456 | hr | ||||
9. | ALA4541705 | 26 | t1/2 | > | 24 | hr | ALA4478455 | hr | ||||
10. | ALA4541705 | 26 | solubility | = | 138 | uM | ALA4478454 | nM | ||||
11. | ALA4541705 | 26 | IC50 | = | 0.061 | uM | ALA4478453 | 7.21 | nM | Human immunodeficiency virus 1 | ||
12. | ALA4541705 | 26 | EC50 | = | 3.7 | uM | ALA4478448 | 5.43 | nM | Human immunodeficiency virus 1 | ||
13. | ALA4541705 | 26 | Ratio CC50/EC50 | = | 70 | ALA4478447 | ||||||
14. | ALA4541705 | 26 | CC50 | = | 58 | uM | ALA4478446 | nM | Homo sapiens | |||
15. | ALA4541705 | 26 | EC50 | = | 0.83 | uM | ALA4478445 | 6.08 | nM | Human immunodeficiency virus 1 | ||
16. | ALA4541705 | 26 | IC50 | = | 0.08 | uM | ALA4478444 | 7.10 | nM | Human immunodeficiency virus 1 | ||
17. | ALA4541705 | 26 | Activity | = | 100 | % | ALA4478442 | % | Human immunodeficiency virus 1 | |||
18. | ALA4541705 | 26 | Activity | = | 98 | % | ALA4478443 | % | Homo sapiens |