# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4543096 | 30f | IC50 | = | 1.87 | uM | ALA4670543 | 5.73 | nM | Marburgvirus | ||
2. | ALA4543096 | 30f | IC50 | = | 1.32 | uM | ALA4670542 | 5.88 | nM | Zaire ebolavirus | ||
3. | ALA4543096 | 30f | Ratio CC50/IC50 | = | 21 | ALA4670541 | ||||||
4. | ALA4543096 | 30f | Ratio CC50/IC50 | = | 15 | ALA4670540 | ||||||
5. | ALA4543096 | 30f | Activity | 0 | ALA4356698 | Active | Homo sapiens | |||||
6. | ALA4543096 | 30f | Activity | 0 | ALA4356697 | Active | ||||||
7. | ALA4543096 | 30f | Activity | 0 | ALA4356696 | Active | ||||||
8. | ALA4543096 | 30f | Drug uptake | = | 588 | nM | ALA4356691 | nM | ||||
9. | ALA4543096 | 30f | Drug uptake | = | 750 | nM | ALA4356690 | nM | ||||
10. | ALA4543096 | 30f | Cp | = | 659 | nM | ALA4356689 | nM | ||||
11. | ALA4543096 | 30f | Cp | = | 786 | nM | ALA4356688 | nM | ||||
12. | ALA4543096 | 30f | Ratio | < | 4 | ALA4356687 | ||||||
13. | ALA4543096 | 30f | IC50 | = | 3.5 | nM | ALA4356686 | 8.46 | nM | Homo sapiens | ||
14. | ALA4543096 | 30f | RBA | = | 59.6 | % | ALA4356685 | % | Homo sapiens | |||
15. | ALA4543096 | 30f | Efficacy | = | 85 | % | ALA4356684 | % | Homo sapiens | |||
16. | ALA4543096 | 30f | pIC50 | = | 8.85 | ALA4356683 | 8.85 | nM | Homo sapiens | |||
17. | ALA4543096 | 30f | Emax | = | 73 | % | ALA4356682 | % | ||||
18. | ALA4543096 | 30f | pIC50 | = | 9.33 | ALA4356681 | 9.33 | nM | ||||
19. | ALA4543096 | 30f | Emax | = | 47 | % | ALA4356680 | % | ||||
20. | ALA4543096 | 30f | pIC50 | = | 8.67 | ALA4356679 | 8.67 | nM |