| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4546264 | 13 | AUC | = | 19500 | nM.hr | ALA4394752 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 2. | ALA4546264 | 13 | beta t1/2 | = | 1.3 | hr | ALA4394750 | hr | ||||
| 3. | ALA4546264 | 13 | Vdss | = | 0.3 | L/Kg | ALA4394749 | L.kg-1 | ||||
| 4. | ALA4546264 | 13 | AUC | = | 4970 | nM.hr | ALA4394748 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 5. | ALA4546264 | 13 | Cmax | = | 10700 | nM | ALA4394747 | nM | ||||
| 6. | ALA4546264 | 13 | F | = | 39 | % | ALA4394738 | % | ||||
| 7. | ALA4546264 | 13 | CL | = | 8.7 | ml/min.Kg | ALA4394735 | mL.min-1.kg-1 | ||||
| 8. | ALA4546264 | 13 | Ratio IC50 | > | 200 | ALA4394739 | ||||||
| 9. | ALA4546264 | 13 | Ratio IC50 | > | 200 | ALA4394740 | ||||||
| 10. | ALA4546264 | 13 | IC50 | = | 55 | uM | ALA4394744 | 4.26 | nM | Homo sapiens | ||
| 11. | ALA4546264 | 13 | IC50 | > | 100 | uM | ALA4394743 | nM | Homo sapiens | |||
| 12. | ALA4546264 | 13 | logPapp | = | -5.2 | ALA4394742 | ||||||
| 13. | ALA4546264 | 13 | IC50 | = | 0.7 | uM | ALA4394741 | 6.16 | nM | Homo sapiens | ||
| 14. | ALA4546264 | 13 | IC50 | = | 0.03 | uM | ALA4394736 | 7.52 | nM | Homo sapiens |
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