# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4548070 | 12 | F | = | 70 | % | ALA4394775 | % | ||||
2. | ALA4548070 | 12 | Tmax | = | 0.8 | hr | ALA4394774 | hr | ||||
3. | ALA4548070 | 12 | Cmax | = | 16500 | nM | ALA4394773 | nM | ||||
4. | ALA4548070 | 12 | AUClast | = | 85000 | nM.hr | ALA4394772 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
5. | ALA4548070 | 12 | t1/2 | = | 3.8 | hr | ALA4394771 | hr | ||||
6. | ALA4548070 | 12 | Vdss | = | 0.8 | L/Kg | ALA4394770 | L.kg-1 | ||||
7. | ALA4548070 | 12 | CL | = | 3.8 | ml/min.Kg | ALA4394769 | mL.min-1.kg-1 | ||||
8. | ALA4548070 | 12 | INH | 0 | ALA4394768 | Not Active | % | Homo sapiens | ||||
9. | ALA4548070 | 12 | INH | 0 | ALA4394767 | Not Active | % | Homo sapiens | ||||
10. | ALA4548070 | 12 | INH | 0 | ALA4394766 | Not Active | % | Homo sapiens | ||||
11. | ALA4548070 | 12 | INH | 0 | ALA4394765 | Not Active | % | Homo sapiens | ||||
12. | ALA4548070 | 12 | Activity | = | 68 | % | ALA4394764 | % | Mus musculus | |||
13. | ALA4548070 | 12 | Activity | = | 86 | % | ALA4394763 | % | Mus musculus | |||
14. | ALA4548070 | 12 | Activity | 0 | ALA4394762 | Dose-dependent effect | Mus musculus | |||||
15. | ALA4548070 | 12 | Time | > | 24 | hr | ALA4394761 | hr | ||||
16. | ALA4548070 | 12 | Ratio AUC | = | 54 | ALA4394760 | ||||||
17. | ALA4548070 | 12 | Ratio | = | 4 | ALA4394759 | ||||||
18. | ALA4548070 | 12 | Drug uptake | 0 | ALA4394758 | Bld | ||||||
19. | ALA4548070 | 12 | Drug uptake | = | 290 | nM | ALA4394757 | nM | ||||
20. | ALA4548070 | 12 | Cp | = | 34 | nM | ALA4394756 | nM |