# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4548492 | 21 | IC50 | <= | 0.1 | uM | ALA4385320 | nM | Homo sapiens | |||
2. | ALA4548492 | 21 | IC50 | <= | 0.1 | uM | ALA4385321 | nM | Homo sapiens | |||
3. | ALA4548492 | 21 | IC50 | <= | 1 | uM | ALA4385322 | nM | Homo sapiens | |||
4. | ALA4548492 | 21 | CL free | = | 104 | L/hr/kg | ALA4324218 | mL.min-1.kg-1 | ||||
5. | ALA4548492 | 21 | CL | = | 4.1 | L/hr/kg | ALA4324217 | mL.min-1.kg-1 | ||||
6. | ALA4548492 | 21 | Fu | = | 4 | % | ALA4324215 | |||||
7. | ALA4548492 | 21 | CLH | = | 13 | ml/min.kg | ALA4324214 | mL.min-1.kg-1 | ||||
8. | ALA4548492 | 21 | CLH | = | 78 | ml/min.kg | ALA4324213 | mL.min-1.kg-1 | ||||
9. | ALA4548492 | 21 | Ratio | = | 21 | ALA4324212 | ||||||
10. | ALA4548492 | 21 | Papp | = | 1.6 | 10'-6 cm/s | ALA4324211 | 10'-6 cm/s | ||||
11. | ALA4548492 | 21 | IC50 | = | 107 | nM | ALA4324210 | 6.97 | nM | Homo sapiens | ||
12. | ALA4548492 | 21 | IC50 | = | 8 | nM | ALA4324209 | 8.10 | nM | Homo sapiens |