# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4549613 | 1 | CHI | = | 4.5 | ALA4307499 | ||||||
2. | ALA4549613 | 1 | Vduss | = | 8.1 | L/Kg | ALA4307500 | L.kg-1 | ||||
3. | ALA4549613 | 1 | CL free | = | 200 | ml/min.kg | ALA4307498 | mL.min-1.kg-1 | ||||
4. | ALA4549613 | 1 | Fu | = | 32 | % | ALA4307497 | |||||
5. | ALA4549613 | 1 | F | = | 63 | % | ALA4307496 | % | ||||
6. | ALA4549613 | 1 | Vdss | = | 2.6 | L/Kg | ALA4307495 | L.kg-1 | ||||
7. | ALA4549613 | 1 | CL | = | 64 | ml/min.kg | ALA4307494 | mL.min-1.kg-1 | ||||
8. | ALA4549613 | 1 | MRT | = | 0.7 | hr | ALA4307493 | hr | ||||
9. | ALA4549613 | 1 | IC50 | = | 5.5 | nM | ALA4307492 | 8.26 | nM | Rattus norvegicus | ||
10. | ALA4549613 | 1 | IC50 | = | 16 | nM | ALA4307491 | 7.80 | nM | Homo sapiens |