| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4553907 | 21 | INH | = | 20 | % | ALA4427375 | % | Rattus norvegicus | |||
| 2. | ALA4553907 | 21 | INH | = | 13 | % | ALA4427374 | % | Rattus norvegicus | |||
| 3. | ALA4553907 | 21 | INH | = | 3 | % | ALA4427373 | % | Rattus norvegicus | |||
| 4. | ALA4553907 | 21 | Drug metabolism | 0 | ALA4427372 | Metabolite_Detected | ||||||
| 5. | ALA4553907 | 21 | AUC | = | 0.13 | uM.hr | ALA4427371 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 6. | ALA4553907 | 21 | AUC | = | 3.64 | uM.hr | ALA4427370 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 7. | ALA4553907 | 21 | F | = | 5 | % | ALA4427369 | % | ||||
| 8. | ALA4553907 | 21 | F | = | 20 | % | ALA4427368 | % | ||||
| 9. | ALA4553907 | 21 | t1/2 | = | 0.3 | hr | ALA4427367 | hr | ||||
| 10. | ALA4553907 | 21 | t1/2 | = | 0.3 | hr | ALA4427366 | hr | ||||
| 11. | ALA4553907 | 21 | Vdss | = | 3.3 | L/Kg | ALA4427365 | L.kg-1 | ||||
| 12. | ALA4553907 | 21 | Vdss | = | 0.66 | L/Kg | ALA4427364 | L.kg-1 | ||||
| 13. | ALA4553907 | 21 | CL | = | 9.4 | L/hr/kg | ALA4427363 | mL.min-1.kg-1 | ||||
| 14. | ALA4553907 | 21 | CL | = | 1.7 | L/hr/kg | ALA4427362 | mL.min-1.kg-1 | ||||
| 15. | ALA4553907 | 21 | INH | = | 40 | % | ALA4427361 | % | Rattus norvegicus | |||
| 16. | ALA4553907 | 21 | INH | 0 | ALA4427360 | Dose-dependent effect | % | Rattus norvegicus | ||||
| 17. | ALA4553907 | 21 | Fu | = | 16 | % | ALA4427355 | |||||
| 18. | ALA4553907 | 21 | Fu | = | 14 | % | ALA4427354 | |||||
| 19. | ALA4553907 | 21 | Fu | = | 28 | % | ALA4427353 | |||||
| 20. | ALA4553907 | 21 | solubility | = | 303 | uM | ALA4427352 | nM |
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