Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4554040	34d	Drug uptake	=	1090	ng/g	ALA4311725			ng/g
2.	ALA4554040	34d	IC50	=	29	nM	ALA4311709	7.54		nM	Homo sapiens
3.	ALA4554040	34d	Emax	=	1	mg kg-1	ALA4311729			mg kg-1	Rattus norvegicus
4.	ALA4554040	34d	Activity		0		ALA4311730		Non-Toxic
5.	ALA4554040	34d	Drug uptake	=	2.7	%	ALA4311728			%
6.	ALA4554040	34d	Drug uptake	=	29.2	ng/g	ALA4311727			ng/g
7.	ALA4554040	34d	Drug uptake	=	104	ng/g	ALA4311726			ng/g
8.	ALA4554040	34d	Activity	=	45.7	%	ALA4311724			%	Rattus norvegicus
9.	ALA4554040	34d	Activity	=	50.8	%	ALA4311723			%	Rattus norvegicus
10.	ALA4554040	34d	Activity	=	27.5	%	ALA4311722			%	Rattus norvegicus
11.	ALA4554040	34d	Drugexcretion	=	65.1	%ID	ALA4311721			%ID
12.	ALA4554040	34d	Drugexcretion	=	18.1	%ID	ALA4311719			%ID
13.	ALA4554040	34d	F	=	0.17	%	ALA4311717			%
14.	ALA4554040	34d	Tmax	=	2.83	hr	ALA4311716			hr
15.	ALA4554040	34d	Cmax	=	1.88	ng/ml	ALA4311715		standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM
16.	ALA4554040	34d	t1/2	=	2.39	hr	ALA4311714			hr
17.	ALA4554040	34d	Vdss	=	1640	ml/kg	ALA4311713			L.kg-1
18.	ALA4554040	34d	CL	=	4020	ml/hr/kg	ALA4311712			mL.min-1.kg-1
19.	ALA4554040	34d	permeability	=	0	10'-6 cm/s	ALA4311711			10'-6 cm/s
20.	ALA4554040	34d	IC50	=	20	nM	ALA4311710	7.70		nM	Homo sapiens