# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4554146 | 7 | AUC | = | 106 | umol/l.hr | ALA4388140 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
2. | ALA4554146 | 7 | t1/2 | = | 3.6 | hr | ALA4388121 | hr | ||||
3. | ALA4554146 | 7 | Cmax | = | 48.1 | umol/L | ALA4388120 | nM | ||||
4. | ALA4554146 | 7 | FC | = | 3.93 | ALA4388139 | Homo sapiens | |||||
5. | ALA4554146 | 7 | Ratio | = | 16.1 | ALA4388138 | ||||||
6. | ALA4554146 | 7 | Ratio | = | 3.3 | ALA4388137 | ||||||
7. | ALA4554146 | 7 | Activity | 0 | ALA4388136 | Active | Homo sapiens | |||||
8. | ALA4554146 | 7 | GI50 | > | 10 | uM | ALA4388135 | nM | Homo sapiens | |||
9. | ALA4554146 | 7 | GI50 | = | 0.47 | uM | ALA4388134 | nM | Homo sapiens | |||
10. | ALA4554146 | 7 | Stability | = | 39.1 | % | ALA4388133 | % | ||||
11. | ALA4554146 | 7 | Stability | = | 39.5 | % | ALA4388132 | % | ||||
12. | ALA4554146 | 7 | Fu | = | 7.7 | % | ALA4388131 | |||||
13. | ALA4554146 | 7 | Fu | = | 1.7 | % | ALA4388130 | |||||
14. | ALA4554146 | 7 | permeability | = | 7.9 | 10'-6 cm/s | ALA4388129 | 10'-6 cm/s | ||||
15. | ALA4554146 | 7 | solubility | = | 76.9 | ug ml-1 | ALA4388128 | ug.mL-1 | ||||
16. | ALA4554146 | 7 | GI50 | = | 2.4 | uM | ALA4388126 | nM | Homo sapiens | |||
17. | ALA4554146 | 7 | IC50 | = | 79.4 | nM | ALA4388125 | 7.10 | nM | Homo sapiens | ||
18. | ALA4554146 | 7 | IC50 | > | 20000 | nM | ALA4388124 | nM | Homo sapiens | |||
19. | ALA4554146 | 7 | IC50 | = | 15.1 | nM | ALA4388123 | 7.82 | nM | Homo sapiens | ||
20. | ALA4554146 | 7 | IC50 | = | 10 | nM | ALA4388122 | 8.00 | nM | Homo sapiens |