# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4556247 | 42b (R) | INH | = | -16 | % | ALA4477906 | % | Rattus norvegicus | |||
2. | ALA4556247 | 42b (R) | INH | = | -5 | % | ALA4477905 | % | Rattus norvegicus | |||
3. | ALA4556247 | 42b (R) | INH | = | -8 | % | ALA4477904 | % | Rattus norvegicus | |||
4. | ALA4556247 | 42b (R) | INH | = | -17 | % | ALA4477903 | % | Rattus norvegicus | |||
5. | ALA4556247 | 42b (R) | INH | = | -3 | % | ALA4477902 | % | Rattus norvegicus | |||
6. | ALA4556247 | 42b (R) | INH | = | -9 | % | ALA4477901 | % | Rattus norvegicus | |||
7. | ALA4556247 | 42b (R) | INH | = | -16 | % | ALA4477900 | % | Rattus norvegicus | |||
8. | ALA4556247 | 42b (R) | INH | = | 22 | % | ALA4477899 | % | Rattus norvegicus | |||
9. | ALA4556247 | 42b (R) | INH | = | 58 | % | ALA4477898 | % | Rattus norvegicus | |||
10. | ALA4556247 | 42b (R) | Activity | 0 | ALA4477892 | Dose-dependent effect | Homo sapiens | |||||
11. | ALA4556247 | 42b (R) | AC50 | = | 61.2 | uM | ALA4477892 | 4.21 | nM | Homo sapiens | ||
12. | ALA4556247 | 42b (R) | MEC | = | 49.6 | uM | ALA4477892 | uM | Homo sapiens | |||
13. | ALA4556247 | 42b (R) | Ratio | = | 0.817 | ALA4477891 | ||||||
14. | ALA4556247 | 42b (R) | Papp | = | 4.74 | ucm/s | ALA4477890 | ucm/s | ||||
15. | ALA4556247 | 42b (R) | Papp | = | 5.8 | ucm/s | ALA4477889 | ucm/s | ||||
16. | ALA4556247 | 42b (R) | t1/2 | = | 5.6 | min | ALA4477888 | hr | ||||
17. | ALA4556247 | 42b (R) | CLH | = | 248 | uL/min | ALA4477886 | uL/min | ||||
18. | ALA4556247 | 42b (R) | Activity | = | 9 | % | ALA4477885 | % | Rattus norvegicus | |||
19. | ALA4556247 | 42b (R) | INH | 0 | ALA4477884 | Dose-dependent effect | % | Rattus norvegicus | ||||
20. | ALA4556247 | 42b (R) | IC50 | = | 2.17 | uM | ALA4477884 | 5.66 | nM | Rattus norvegicus |