# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4558167 | 10l; JR10 | EC50 | > | 100 | uM | ALA4380983 | nM | Homo sapiens | |||
2. | ALA4558167 | 10l; JR10 | pIC50 | = | 7.5 | ALA4380985 | 7.50 | nM | Homo sapiens | |||
3. | ALA4558167 | 10l; JR10 | Activity | = | 45 | % | ALA4381003 | % | Rattus norvegicus | |||
4. | ALA4558167 | 10l; JR10 | Cmax | = | 143 | ng/ml | ALA4380998 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
5. | ALA4558167 | 10l; JR10 | Tmax | = | 240 | min | ALA4380997 | hr | ||||
6. | ALA4558167 | 10l; JR10 | AUC | = | 814 | ng.hr/ml | ALA4380996 | ng.hr.mL-1 | ||||
7. | ALA4558167 | 10l; JR10 | CL | = | 4.6 | ml/min.Kg | ALA4380995 | mL.min-1.kg-1 | ||||
8. | ALA4558167 | 10l; JR10 | beta t1/2 | = | 61 | min | ALA4380982 | hr | ||||
9. | ALA4558167 | 10l; JR10 | Vd | = | 0.3 | l | ALA4380981 | l | ||||
10. | ALA4558167 | 10l; JR10 | AUC | = | 1802 | ng.hr/ml | ALA4380980 | ng.hr.mL-1 | ||||
11. | ALA4558167 | 10l; JR10 | Stability | 0 | ALA4380991 | Stable | % | |||||
12. | ALA4558167 | 10l; JR10 | Stability | 0 | ALA4380989 | Stable | % | |||||
13. | ALA4558167 | 10l; JR10 | pEC50 | < | 4 | ALA4380983 | nM | Homo sapiens | ||||
14. | ALA4558167 | 10l; JR10 | IC50 | = | 0.03 | uM | ALA4380985 | 7.52 | nM | Homo sapiens |