| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4558865 | 26 | t1/2 | = | 8.67 | hr | ALA4394472 | hr | ||||
| 2. | ALA4558865 | 26 | AUC | = | 24481 | ug/L.hr | ALA4394471 | ng.hr.mL-1 | ||||
| 3. | ALA4558865 | 26 | F | = | 52 | % | ALA4394466 | % | ||||
| 4. | ALA4558865 | 26 | AUCt | = | 21645 | ug/L.hr | ALA4394465 | ng.hr.mL-1 | ||||
| 5. | ALA4558865 | 26 | Tmax | = | 5.33 | hr | ALA4394464 | hr | ||||
| 6. | ALA4558865 | 26 | Cmax | = | 1425 | ug/L | ALA4394463 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 7. | ALA4558865 | 26 | Vz | = | 3544 | mg kg-1 | ALA4394462 | mg kg-1 | ||||
| 8. | ALA4558865 | 26 | CL | = | 193.73 | ml/hr/kg | ALA4394461 | mL.min-1.kg-1 | ||||
| 9. | ALA4558865 | 26 | t1/2 | = | 12.71 | hr | ALA4394460 | hr | ||||
| 10. | ALA4558865 | 26 | AUC | = | 10352 | ug/L.hr | ALA4394459 | ng.hr.mL-1 | ||||
| 11. | ALA4558865 | 26 | AUCt | = | 7660 | ug/L.hr | ALA4394458 | ng.hr.mL-1 | ||||
| 12. | ALA4558865 | 26 | Tmax | = | 0.08 | hr | ALA4394457 | hr | ||||
| 13. | ALA4558865 | 26 | Cmax | = | 980 | ug/L | ALA4394456 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 14. | ALA4558865 | 26 | Stability | = | 78 | % | ALA4394455 | % | ||||
| 15. | ALA4558865 | 26 | Activity | 0 | ALA4394454 | Active | Homo sapiens | |||||
| 16. | ALA4558865 | 26 | Activity | 0 | ALA4394453 | Active | Homo sapiens | |||||
| 17. | ALA4558865 | 26 | INH | 0 | ALA4394452 | Dose-dependent effect | % | Homo sapiens | ||||
| 18. | ALA4558865 | 26 | IC50 | = | 21.84 | uM | ALA4394427 | 4.66 | nM | Homo sapiens | ||
| 19. | ALA4558865 | 26 | IC50 | = | 41.23 | uM | ALA4394428 | 4.38 | nM | Homo sapiens | ||
| 20. | ALA4558865 | 26 | IC50 | = | 13.82 | uM | ALA4394429 | 4.86 | nM | Homo sapiens |
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