# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4559701 | 3 | Ratio | = | 0.7 | ALA4399601 | ||||||
2. | ALA4559701 | 3 | permeability | = | 36 | 10'-6 cm/s | ALA4399581 | 10'-6 cm/s | ||||
3. | ALA4559701 | 3 | Vdss | = | 0.94 | L/Kg | ALA4399597 | L.kg-1 | ||||
4. | ALA4559701 | 3 | t1/2 | = | 4.6 | hr | ALA4399596 | hr | ||||
5. | ALA4559701 | 3 | CL | = | 12 | ml/min.kg | ALA4399595 | mL.min-1.kg-1 | ||||
6. | ALA4559701 | 3 | CL free | = | 172 | uL/min | ALA4399594 | uL/min | ||||
7. | ALA4559701 | 3 | CL free | = | 58 | uL/min | ALA4399593 | uL/min | ||||
8. | ALA4559701 | 3 | Ki | = | 270 | nM | ALA4399592 | 6.57 | nM | Homo sapiens | ||
9. | ALA4559701 | 3 | Ki | = | 560 | nM | ALA4399589 | 6.25 | nM | Homo sapiens | ||
10. | ALA4559701 | 3 | Ki | = | 584 | nM | ALA4399586 | 6.23 | nM | Homo sapiens | ||
11. | ALA4559701 | 3 | Ki | 0 | ALA4399585 | Not Determined | Homo sapiens | |||||
12. | ALA4559701 | 3 | Ki | = | 28 | nM | ALA4399584 | 7.55 | nM | Homo sapiens |