| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4560617 | 11 | INH | 0 | ALA4398890 | Active | % | hepatitis B virus genotype D | ||||
| 2. | ALA4560617 | 11 | Activity | 0 | ALA4398887 | Non-Toxic | ||||||
| 3. | ALA4560617 | 11 | log(activity) | = | 1.1 | ALA4398892 | hepatitis B virus genotype D | |||||
| 4. | ALA4560617 | 11 | INH | 0 | ALA4398889 | Dose-dependent effect | % | hepatitis B virus genotype D | ||||
| 5. | ALA4560617 | 11 | Activity | 0 | ALA4398886 | Non-Toxic | ||||||
| 6. | ALA4560617 | 11 | log(activity) | = | 3.2 | ALA4398884 | Hepatitis B virus | |||||
| 7. | ALA4560617 | 11 | INH | 0 | ALA4398883 | Dose-dependent effect | % | Hepatitis B virus | ||||
| 8. | ALA4560617 | 11 | Ratio | = | 3 | ALA4398881 | Rattus norvegicus | |||||
| 9. | ALA4560617 | 11 | Ratio | = | 7 | ALA4398880 | Rattus norvegicus | |||||
| 10. | ALA4560617 | 11 | F | = | 10.3 | % | ALA4398879 | % | ||||
| 11. | ALA4560617 | 11 | AUC | = | 6524 | ng/mL.hr | ALA4398878 | ng.hr.mL-1 | ||||
| 12. | ALA4560617 | 11 | Cmax | = | 2882 | ng/ml | ALA4398877 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 13. | ALA4560617 | 11 | Tmax | = | 0.582 | hr | ALA4398876 | hr | ||||
| 14. | ALA4560617 | 11 | t1/2 | = | 1.3 | hr | ALA4398875 | hr | ||||
| 15. | ALA4560617 | 11 | Ratio IC50 | = | 22 | ALA4398861 | Hepatitis B virus | |||||
| 16. | ALA4560617 | 11 | Ratio IC50 | = | 3 | ALA4398860 | Hepatitis B virus | |||||
| 17. | ALA4560617 | 11 | Ratio CC50/IC50 | = | 80 | ALA4398859 | ||||||
| 18. | ALA4560617 | 11 | CC50 | = | 57.28 | uM | ALA4398857 | nM | Homo sapiens | |||
| 19. | ALA4560617 | 11 | IC50 | = | 0.71 | uM | ALA4398858 | 6.15 | nM | Hepatitis B virus |
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