# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4561925 | 41 | BPR | = | 8.81 | ALA4355773 | ||||||
2. | ALA4561925 | 41 | Drug uptake | = | 0.193 | nmol/g | ALA4355771 | nmol/g | ||||
3. | ALA4561925 | 41 | FC | = | 1.81 | ALA4355769 | Rattus norvegicus | |||||
4. | ALA4561925 | 41 | F | = | 44.8 | % | ALA4355768 | % | ||||
5. | ALA4561925 | 41 | Vdss | = | 5.99 | L/Kg | ALA4355765 | L.kg-1 | ||||
6. | ALA4561925 | 41 | t1/2 | = | 3.89 | hr | ALA4355762 | hr | ||||
7. | ALA4561925 | 41 | CL | = | 72.6 | ml/min.kg | ALA4355760 | mL.min-1.kg-1 | ||||
8. | ALA4561925 | 41 | AUC/dose | = | 0.376 | uM.hr.kg/mg | ALA4355759 | uM.hr.kg/mg | ||||
9. | ALA4561925 | 41 | EC50 | = | 41.4 | nM | ALA4355755 | 7.38 | nM | Rattus norvegicus | ||
10. | ALA4561925 | 41 | Ki | = | 5.3 | nM | ALA4355754 | 8.28 | nM | Homo sapiens | ||
11. | ALA4561925 | 41 | Papp | = | 14 | 10'-6 cm/s | ALA4355751 | 10'-6 cm/s | ||||
12. | ALA4561925 | 41 | Ki | > | 10000 | nM | ALA4355756 | nM | Homo sapiens |