| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4564092 | 56 | t1/2 | = | 4.6 | hr | ALA4380474 | hr | ||||
| 2. | ALA4564092 | 56 | F | = | 40.9 | % | ALA4380452 | % | ||||
| 3. | ALA4564092 | 56 | AUC | = | 654.2 | ng.hr/ml | ALA4380451 | ng.hr.mL-1 | ||||
| 4. | ALA4564092 | 56 | Cmax | = | 365 | ng/ml | ALA4380450 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 5. | ALA4564092 | 56 | t1/2 | = | 3.3 | hr | ALA4380449 | hr | ||||
| 6. | ALA4564092 | 56 | CL | = | 3 | L/hr/kg | ALA4380448 | mL.min-1.kg-1 | ||||
| 7. | ALA4564092 | 56 | Vz | = | 14.5 | L/Kg | ALA4380447 | L.kg-1 | ||||
| 8. | ALA4564092 | 56 | Vdss | = | 4 | L/Kg | ALA4380446 | L.kg-1 | ||||
| 9. | ALA4564092 | 56 | AUC | = | 331.6 | ng.hr/ml | ALA4380445 | ng.hr.mL-1 | ||||
| 10. | ALA4564092 | 56 | Cmax | = | 808.1 | ng/ml | ALA4380444 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 11. | ALA4564092 | 56 | INH | 0 | ALA4380443 | Not Active | % | Homo sapiens | ||||
| 12. | ALA4564092 | 56 | INH | = | 63 | % | ALA4380426 | % | Homo sapiens | |||
| 13. | ALA4564092 | 56 | INH | = | 25 | % | ALA4380427 | % | Homo sapiens | |||
| 14. | ALA4564092 | 56 | INH | = | 48 | % | ALA4380442 | % | Homo sapiens | |||
| 15. | ALA4564092 | 56 | INH | = | 28 | % | ALA4380441 | % | Homo sapiens | |||
| 16. | ALA4564092 | 56 | INH | = | 21 | % | ALA4380440 | % | Homo sapiens | |||
| 17. | ALA4564092 | 56 | Stability | = | 75.5 | % | ALA4380439 | % | ||||
| 18. | ALA4564092 | 56 | CLH | < | 9.6 | microL/min/mg | ALA4380438 | mL.min-1.g-1 | ||||
| 19. | ALA4564092 | 56 | t1/2 | > | 145 | min | ALA4380437 | hr | ||||
| 20. | ALA4564092 | 56 | Stability | = | 105.8 | % | ALA4380436 | % |
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