| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  AR 420626 | 16; AR420626 | INH | 0 | ALA4404882 | Not Active | % | Homo sapiens | ||||
| 2. | AR 420626 | 16; AR420626 | Activity | 0 | ALA4404881 | Not Active | Homo sapiens | |||||
| 3. | AR 420626 | 16; AR420626 | Activity | 0 | ALA4404880 | Not Active | Homo sapiens | |||||
| 4. | AR 420626 | 16; AR420626 | Activity | 0 | ALA4404879 | Not Active | Homo sapiens | |||||
| 5. | AR 420626 | 16; AR420626 | Activity | 0 | ALA4404878 | Not Active | Homo sapiens | |||||
| 6. | AR 420626 | 16; AR420626 | pEC50 | = | 5.88 | ALA4404877 | 5.88 | nM | Mus musculus | |||
| 7. | AR 420626 | 16; AR420626 | pEC50 | = | 6.34 | ALA4404876 | 6.34 | nM | Rattus norvegicus | |||
| 8. | AR 420626 | 16; AR420626 | F | = | 88 | % | ALA4404875 | % | ||||
| 9. | AR 420626 | 16; AR420626 | AUC | = | 423000 | ng.min/ml | ALA4404874 | ng.hr.mL-1 | ||||
| 10. | AR 420626 | 16; AR420626 | Cmax | = | 5740 | ng/ml | ALA4404873 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 11. | AR 420626 | 16; AR420626 | Tmax | = | 30 | min | ALA4404872 | hr | ||||
| 12. | AR 420626 | 16; AR420626 | t1/2 | = | 60.8 | min | ALA4404871 | hr | ||||
| 13. | AR 420626 | 16; AR420626 | CL | = | 19.6 | ml/min.kg | ALA4404870 | mL.min-1.kg-1 | ||||
| 14. | AR 420626 | 16; AR420626 | Vd | = | 629 | ml/kg | ALA4404869 | L.kg-1 | ||||
| 15. | AR 420626 | 16; AR420626 | t1/2 | = | 22.3 | min | ALA4404868 | hr | ||||
| 16. | AR 420626 | 16; AR420626 | Stability | = | 1 | % | ALA4404867 | % | ||||
| 17. | AR 420626 | 16; AR420626 | Emax | = | 106 | % | ALA4404863 | % | Homo sapiens | |||
| 18. | AR 420626 | 16; AR420626 | pEC50 | = | 6.89 | ALA4404862 | 6.89 | nM | Homo sapiens | |||
| 19. | AR 420626 | 16; AR420626 | Emax | = | 120 | % | ALA4404861 | % | Homo sapiens | |||
| 20. | AR 420626 | 16; AR420626 | pEC50 | = | 5.74 | ALA4404860 | 5.74 | nM | Homo sapiens |
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