# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4564985 | 38 | Activity | 0 | ALA4370935 | Active | Rattus norvegicus | |||||
2. | ALA4564985 | 38 | Activity | 0 | ALA4370934 | Active | Rattus norvegicus | |||||
3. | ALA4564985 | 38 | INH | = | 47 | % | ALA4370933 | % | Rattus norvegicus | |||
4. | ALA4564985 | 38 | Drug uptake | = | 40 | uM | ALA4370932 | uM | ||||
5. | ALA4564985 | 38 | Drug uptake | <= | 17 | uM | ALA4370931 | uM | ||||
6. | ALA4564985 | 38 | Activity | 0 | ALA4370930 | Non-Toxic | ||||||
7. | ALA4564985 | 38 | Activity | 0 | ALA4370929 | Non-Toxic | ||||||
8. | ALA4564985 | 38 | Activity | 0 | ALA4370928 | Non-Toxic | Canis lupus familiaris | |||||
9. | ALA4564985 | 38 | Activity | 0 | ALA4370927 | Non-Toxic | ||||||
10. | ALA4564985 | 38 | Activity | 0 | ALA4370926 | Non-Toxic | ||||||
11. | ALA4564985 | 38 | Activity | 0 | ALA4370925 | Non-Toxic | Cavia porcellus | |||||
12. | ALA4564985 | 38 | t1/2 lambda z | = | 8.2 | day | ALA4370924 | hr | ||||
13. | ALA4564985 | 38 | AUC | = | 55.6 | microg.hr/mL | ALA4370923 | ng.hr.mL-1 | ||||
14. | ALA4564985 | 38 | Tmax | = | 8 | day | ALA4370922 | hr | ||||
15. | ALA4564985 | 38 | Cmax | = | 3.08 | ug ml-1 | ALA4370921 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
16. | ALA4564985 | 38 | Ratio AUC | = | 0.8 | ALA4370920 | ||||||
17. | ALA4564985 | 38 | Ratio AUC | = | 0.7 | ALA4370879 | ||||||
18. | ALA4564985 | 38 | t1/2 lambda z | = | 8.1 | day | ALA4370919 | hr | ||||
19. | ALA4564985 | 38 | AUC | = | 70.3 | microg.hr/mL | ALA4370918 | ng.hr.mL-1 | ||||
20. | ALA4564985 | 38 | Tmax | = | 1 | day | ALA4370917 | hr |