# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4568508 | 7a | Papp | = | 33 | 10'-6 cm/s | ALA4403255 | 10'-6 cm/s | ||||
2. | ALA4568508 | 7a | Papp | = | 23 | 10'-6 cm/s | ALA4403254 | 10'-6 cm/s | ||||
3. | ALA4568508 | 7a | F | 0 | ALA4403249 | Not Determined | % | |||||
4. | ALA4568508 | 7a | t1/2 | = | 0.89 | hr | ALA4403248 | hr | ||||
5. | ALA4568508 | 7a | AUC | = | 21.61 | uM.hr | ALA4403247 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
6. | ALA4568508 | 7a | Cmax | = | 32.03 | uM | ALA4403246 | nM | ||||
7. | ALA4568508 | 7a | Stability | = | 100 | % | ALA4403244 | % | ||||
8. | ALA4568508 | 7a | IC50 | = | 10 | uM | ALA4403243 | 5.00 | nM | Homo sapiens | ||
9. | ALA4568508 | 7a | IC50 | = | 1.2 | uM | ALA4403242 | 5.92 | nM | Homo sapiens | ||
10. | ALA4568508 | 7a | IC50 | > | 100 | uM | ALA4403241 | nM | Sus scrofa | |||
11. | ALA4568508 | 7a | IC50 | > | 100 | uM | ALA4403240 | nM | Homo sapiens | |||
12. | ALA4568508 | 7a | IC50 | = | 59.3 | uM | ALA4403239 | 4.23 | nM | Homo sapiens | ||
13. | ALA4568508 | 7a | Ratio IC50 | >= | 10 | ALA4403238 | ||||||
14. | ALA4568508 | 7a | IC50 | = | 0.86 | uM | ALA4403237 | 6.07 | nM | Homo sapiens | ||
15. | ALA4568508 | 7a | IC50 | = | 1.49 | uM | ALA4403236 | 5.83 | nM | |||
16. | ALA4568508 | 7a | Ratio IC50 | <= | 7 | ALA4403234 | Homo sapiens | |||||
17. | ALA4568508 | 7a | IC50 | = | 0.069 | uM | ALA4403233 | 7.16 | nM | Homo sapiens | ||
18. | ALA4568508 | 7a | IC50 | = | 0.086 | uM | ALA4403232 | 7.07 | nM | Homo sapiens | ||
19. | ALA4568508 | 7a | IC50 | = | 0.587 | uM | ALA4403231 | 6.23 | nM | Homo sapiens |