# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4569641 | 13 | INH | = | 6.9 | uM | ALA4478742 | uM | Homo sapiens | |||
2. | ALA4569641 | 13 | EC50 | = | 2.4 | uM | ALA4478760 | 5.62 | nM | Plasmodium falciparum | ||
3. | ALA4569641 | 13 | EC50 | > | 10 | uM | ALA4478759 | nM | Plasmodium falciparum | |||
4. | ALA4569641 | 13 | Activity | 0 | ALA4478758 | Active | Plasmodium falciparum | |||||
5. | ALA4569641 | 13 | INH | = | 27 | uM | ALA4478757 | uM | Plasmodium falciparum | |||
6. | ALA4569641 | 13 | Activity | = | 99.9 | % | ALA4478756 | % | Plasmodium falciparum | |||
7. | ALA4569641 | 13 | Activity | 0 | ALA4478755 | Active | Plasmodium falciparum | |||||
8. | ALA4569641 | 13 | AUCED90 | = | 1.4 | microg.hr/mL | ALA4478754 | microg.hr/mL | Plasmodium falciparum | |||
9. | ALA4569641 | 13 | Activity | 0 | ALA4478753 | Active | Plasmodium falciparum | |||||
10. | ALA4569641 | 13 | Activity | 0 | ALA4478752 | Active | Plasmodium falciparum | |||||
11. | ALA4569641 | 13 | ED90 | = | 11.7 | mg kg-1 | ALA4478751 | mg kg-1 | Plasmodium falciparum | |||
12. | ALA4569641 | 13 | IC50 | = | 0.1 | uM | ALA4478741 | 7.00 | nM | Homo sapiens | ||
13. | ALA4569641 | 13 | IC50 | = | 0.7 | uM | ALA4478740 | 6.16 | nM | Homo sapiens | ||
14. | ALA4569641 | 13 | IC50 | = | 38 | uM | ALA4478739 | 4.42 | nM | Homo sapiens | ||
15. | ALA4569641 | 13 | IC50 | = | 3.5 | uM | ALA4478738 | 5.46 | nM | Homo sapiens | ||
16. | ALA4569641 | 13 | IC50 | > | 100 | uM | ALA4478737 | nM | Homo sapiens | |||
17. | ALA4569641 | 13 | PPB | = | 78 | % | ALA4478736 | % | ||||
18. | ALA4569641 | 13 | EC50 | = | 0.28 | uM | ALA4478735 | 6.55 | nM | Plasmodium falciparum | ||
19. | ALA4569641 | 13 | Kinetic_solubility | = | 106 | uM | ALA4478734 | nM | ||||
20. | ALA4569641 | 13 | CLH | = | 3 | ml/min/g | ALA4478733 | mL.min-1.g-1 |