# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4571666 | 18 | Drug metabolism | 0 | ALA4339685 | Metabolite_Detected | ||||||
2. | ALA4571666 | 18 | Drug metabolism | 0 | ALA4339684 | Metabolite_Detected | ||||||
3. | ALA4571666 | 18 | Drug metabolism | 0 | ALA4339683 | Metabolite_Detected | ||||||
4. | ALA4571666 | 18 | CLH | = | 70 | ml/min.kg | ALA4339672 | mL.min-1.kg-1 | ||||
5. | ALA4571666 | 18 | Tmax | = | 0.5 | hr | ALA4339671 | hr | ||||
6. | ALA4571666 | 18 | AUC | = | 372 | hr.ng/ml | ALA4339670 | ng.hr.mL-1 | ||||
7. | ALA4571666 | 18 | Cmax | = | 227 | ng/ml | ALA4339669 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
8. | ALA4571666 | 18 | Vdss | = | 1.6 | L/Kg | ALA4339668 | L.kg-1 | ||||
9. | ALA4571666 | 18 | CL | = | 167 | ml/min.kg | ALA4339667 | mL.min-1.kg-1 | ||||
10. | ALA4571666 | 18 | Ratio | = | 4 | ALA4339666 | ||||||
11. | ALA4571666 | 18 | IC50 | > | 10 | uM | ALA4339665 | nM | Homo sapiens | |||
12. | ALA4571666 | 18 | ERH | = | 0.65 | ALA4339664 | ||||||
13. | ALA4571666 | 18 | IC50 | > | 10 | uM | ALA4339663 | nM | Homo sapiens | |||
14. | ALA4571666 | 18 | IC50 | > | 10 | uM | ALA4339662 | nM | Homo sapiens | |||
15. | ALA4571666 | 18 | IC50 | > | 10 | uM | ALA4339661 | nM | Homo sapiens | |||
16. | ALA4571666 | 18 | IC50 | > | 10 | uM | ALA4339660 | nM | Homo sapiens | |||
17. | ALA4571666 | 18 | IC50 | > | 10 | uM | ALA4339659 | nM | Homo sapiens | |||
18. | ALA4571666 | 18 | IC50 | > | 10 | uM | ALA4339658 | nM | Homo sapiens | |||
19. | ALA4571666 | 18 | ERH | = | 0.77 | ALA4339657 | ||||||
20. | ALA4571666 | 18 | IC50 | = | 81 | nM | ALA4339649 | 7.09 | nM | Homo sapiens |