# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4572210 | BAY-771 | solubility | > | 412 | mg/L | ALA5217609 | ug.mL-1 | ||||
2. | ALA4572210 | BAY-771 | logD | = | 2.2 | ALA5217608 | ||||||
3. | ALA4572210 | BAY-771 | IC50 | = | 6200 | nM | ALA5217600 | 5.21 | nM | |||
4. | ALA4572210 | BAY-771 | Papp | = | 171 | nm/s | ALA5217596 | nm/s | ||||
5. | ALA4572210 | BAY-771 | F | = | 40 | % | ALA5217595 | % | ||||
6. | ALA4572210 | BAY-771 | F | = | 40 | % | ALA5217594 | % | ||||
7. | ALA4572210 | BAY-771 | CLH | = | 2.5 | L/hr/kg | ALA5217593 | mL.min-1.kg-1 | ||||
8. | ALA4572210 | BAY-771 | CLH | = | 0.79 | L/hr/kg | ALA5217592 | mL.min-1.kg-1 | ||||
9. | ALA4572210 | BAY-771 | pKa | = | 5.2 | ALA5217585 | ||||||
10. | ALA4572210 | BAY-771 | Ratio | = | 0.62 | ALA5217584 | ||||||
11. | ALA4572210 | BAY-771 | Papp | = | 275 | nm/s | ALA5217583 | nm/s | ||||
12. | ALA4572210 | BAY-771 | IC50 | = | 10800 | nM | ALA5217582 | 4.97 | nM | Homo sapiens | ||
13. | ALA4572210 | BAY-771 | IC50 | = | 6500 | nM | ALA5217581 | 5.19 | nM | Homo sapiens | ||
14. | ALA4572210 | BAY-771 | IC50 | 6.2 | uM | ALA4885538 | Not Active | nM | Homo sapiens | |||
15. | ALA4572210 | BAY-771 | IC50 | 10.8 | uM | ALA4885535 | Not Active | nM | Homo sapiens | |||
16. | ALA4572210 | BAY-771 | IC50 | 6.5 | uM | ALA4885534 | Not Active | nM | Homo sapiens |