| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  6-(3-methyl-1H-pyrazol-4-yl)-2-[(2R)-quinuclidin-2-yl]-3H-thieno[3,2-d]pyrimidin-4-one | 11c | Ratio IC50 | = | 460 | ALA4325329 | ||||||
| 2. | 6-(3-methyl-1H-pyrazol-4-yl)-2-[(2R)-quinuclidin-2-yl]-3H-thieno[3,2-d]pyrimidin-4-one | 11c | Ratio IC50 | = | 10000 | ALA4325328 | ||||||
| 3. | 6-(3-methyl-1H-pyrazol-4-yl)-2-[(2R)-quinuclidin-2-yl]-3H-thieno[3,2-d]pyrimidin-4-one | 11c | IC50 | = | 460 | nM | ALA4325327 | 6.34 | nM | Homo sapiens | ||
| 4. | 6-(3-methyl-1H-pyrazol-4-yl)-2-[(2R)-quinuclidin-2-yl]-3H-thieno[3,2-d]pyrimidin-4-one | 11c | IC50 | > | 10000 | nM | ALA4325326 | nM | Homo sapiens | |||
| 5. | 6-(3-methyl-1H-pyrazol-4-yl)-2-[(2R)-quinuclidin-2-yl]-3H-thieno[3,2-d]pyrimidin-4-one | 11c | IC50 | = | 1 | nM | ALA4325325 | 9.00 | nM | Homo sapiens |
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