# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA146227 | 6j | Stability | < | 1 | % | ALA3384565 | % | ||||
2. | ALA146227 | 6j | Stability | < | 1 | % | ALA3384562 | % | ||||
3. | ALA146227 | 6j | IC50 | = | 0.1 | uM | ALA3807134 | 7.00 | nM | Sus scrofa | ||
4. | ALA146227 | 6j | IC50 | = | 94 | nM | ALA3807135 | 7.03 | nM | Rattus norvegicus | ||
5. | ALA146227 | 6j | IC50 | = | 43 | nM | ALA3807136 | 7.37 | nM | Homo sapiens | ||
6. | ALA146227 | 6j | Kd | = | 0.15 | uM | ALA4221098 | 6.82 | nM | Sus scrofa | ||
7. | ALA146227 | 6j | IC50 | = | 24 | uM | ALA2388919 | 4.62 | nM | |||
8. | ALA146227 | 6j | IC50 | = | 6.9 | nM | ALA2343135 | 8.16 | nM | Homo sapiens | ||
9. | ALA146227 | 6j | Peff | = | 18.2 | ucm/s | ALA2343134 | ucm/s | ||||
10. | ALA146227 | 6j | IC50 | = | 42 | nM | ALA2343128 | 7.38 | nM | Homo sapiens | ||
11. | ALA146227 | 6j | Ratio IC50 | = | 12 | ALA2032839 | ||||||
12. | ALA146227 | 6j | Ratio IC50 | = | 12 | ALA2032838 | Human immunodeficiency virus 1 | |||||
13. | ALA146227 | 6j | CC50 | = | 115 | uM | ALA2032834 | nM | Homo sapiens | |||
14. | ALA146227 | 6j | EC50 | > | 115 | uM | ALA2032833 | nM | Human immunodeficiency virus 1 | |||
15. | ALA146227 | 6j | INH | = | 97 | % | ALA2032832 | % | Human immunodeficiency virus 1 | |||
16. | ALA146227 | 6j | IC50 | > | 100 | uM | ALA2032831 | nM | Human immunodeficiency virus 1 | |||
17. | ALA146227 | 6j | pKa | = | 8.7 | ALA939022 | ||||||
18. | ALA146227 | 6j | Ratio | = | 14 | ALA939025 | ||||||
19. | ALA146227 | 6j | Ratio IC50 | = | 10 | ALA939020 | ||||||
20. | ALA146227 | 6j | Drug uptake | = | 15 | nM | ALA939018 | nM | Rattus norvegicus |