# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4577379 | 12 | CL | = | 31 | % | ALA4356639 | % | ||||
2. | ALA4577379 | 12 | Papp | = | 4.5 | ucm/s | ALA4356638 | ucm/s | ||||
3. | ALA4577379 | 12 | CL | = | 1.4 | L/hr/kg | ALA4356601 | mL.min-1.kg-1 | ||||
4. | ALA4577379 | 12 | Ki | = | 0.09 | nM | ALA4356587 | 10.05 | nM | Homo sapiens | ||
5. | ALA4577379 | 12 | IC50 | = | 0.5 | nM | ALA4356586 | 9.30 | nM | Homo sapiens | ||
6. | ALA4577379 | 12 | F | = | 0 | % | ALA4356597 | % | ||||
7. | ALA4577379 | 12 | t1/2 | = | 6.8 | hr | ALA4356596 | hr | ||||
8. | ALA4577379 | 12 | Stability | = | 100 | % | ALA4356593 | % | ||||
9. | ALA4577379 | 12 | Stability | = | 100 | % | ALA4356592 | % | ||||
10. | ALA4577379 | 12 | Stability | = | 26 | % | ALA4356591 | % | ||||
11. | ALA4577379 | 12 | Stability | = | 49 | % | ALA4356590 | % | ||||
12. | ALA4577379 | 12 | IC50 | = | 58 | nM | ALA4356588 | 7.24 | nM | Homo sapiens |