# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4586417 | 26 | CLH | = | 316.8 | L/hr/kg | ALA4479916 | mL.min-1.kg-1 | ||||
2. | ALA4586417 | 26 | CLH | = | 0.176 | ml/min | ALA4479915 | ml/min | ||||
3. | ALA4586417 | 26 | t1/2 | = | 7.52 | min | ALA4479914 | hr | ||||
4. | ALA4586417 | 26 | Kel | = | 0.088 | /min | ALA4479913 | /min | ||||
5. | ALA4586417 | 26 | Ratio IC50 | = | 9.5 | ALA4479904 | Homo sapiens | |||||
6. | ALA4586417 | 26 | Ratio IC50 | <= | 5.7 | ALA4479905 | Homo sapiens | |||||
7. | ALA4586417 | 26 | Ratio IC50 | <= | 9.3 | ALA4479908 | Mus musculus | |||||
8. | ALA4586417 | 26 | Ratio IC50 | <= | 8.3 | ALA4479907 | Homo sapiens | |||||
9. | ALA4586417 | 26 | Ratio IC50 | = | 1 | ALA4479906 | Homo sapiens | |||||
10. | ALA4586417 | 26 | PPB | = | 81.24 | % | ALA4479903 | % | ||||
11. | ALA4586417 | 26 | Drug metabolism | = | 46 | % | ALA4479896 | % | ||||
12. | ALA4586417 | 26 | solubility | = | 2.08 | mg/L | ALA4479895 | ug.mL-1 | ||||
13. | ALA4586417 | 26 | Stability | = | 96 | % | ALA4479894 | % | ||||
14. | ALA4586417 | 26 | Stability | = | 65 | % | ALA4479892 | % | ||||
15. | ALA4586417 | 26 | Stability | = | 85 | % | ALA4479884 | % | ||||
16. | ALA4586417 | 26 | INH | = | 100 | % | ALA4479891 | % | Homo sapiens | |||
17. | ALA4586417 | 26 | Activity | 0 | ALA4479889 | Active | Homo sapiens | |||||
18. | ALA4586417 | 26 | Activity | 0 | ALA4479887 | Active | Homo sapiens | |||||
19. | ALA4586417 | 26 | Activity | 0 | ALA4479885 | Active | Homo sapiens | |||||
20. | ALA4586417 | 26 | Activity | 0 | ALA4479882 | Dose-dependent effect | Homo sapiens |