| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4588661 | 16 | Vdss | = | 16 | L/Kg | ALA5165212 | L.kg-1 | ||||
| 2. | ALA4588661 | 16 | AUC | = | 642 | hr.ng/ml | ALA5165211 | ng.hr.mL-1 | ||||
| 3. | ALA4588661 | 16 | Selectivity ratio | = | 210 | ALA5165210 | ||||||
| 4. | ALA4588661 | 16 | GI50 | = | 78 | nM | ALA5165208 | nM | Homo sapiens | |||
| 5. | ALA4588661 | 16 | Activity | 0 | ALA5165206 | Toxic | ||||||
| 6. | ALA4588661 | 16 | Activity | 0 | ALA5165205 | Toxic | ||||||
| 7. | ALA4588661 | 16 | Activity | 0 | ALA5165204 | Toxic | ||||||
| 8. | ALA4588661 | 16 | CL | = | 78 | ml/min.kg | ALA5165203 | mL.min-1.kg-1 | ||||
| 9. | ALA4588661 | 16 | permeability | < | 0.6 | 10^-6 cm/s | ALA5165202 | 10^-6 cm/s | ||||
| 10. | ALA4588661 | 16 | Kinetic_solubility | = | 29 | uM | ALA5165201 | nM | ||||
| 11. | ALA4588661 | 16 | GI50 | = | 8000 | nM | ALA5165200 | nM | Homo sapiens | |||
| 12. | ALA4588661 | 16 | GI50 | = | 38 | nM | ALA5165199 | nM | Homo sapiens | |||
| 13. | ALA4588661 | 16 | Ki | < | 0.02 | nM | ALA5165198 | nM | Homo sapiens | |||
| 14. | ALA4588661 | 16 | CL | 0 | ALA5165190 | Bld | ||||||
| 15. | ALA4588661 | 16 | Activity | = | 8.8 | % | ALA4380516 | % | Homo sapiens | |||
| 16. | ALA4588661 | 16 | Activity | = | 9 | % | ALA4380515 | % | Homo sapiens | |||
| 17. | ALA4588661 | 16 | Activity | = | 60 | % | ALA4380514 | % | Homo sapiens | |||
| 18. | ALA4588661 | 16 | Activity | = | 22.9 | % | ALA4380513 | % | Homo sapiens | |||
| 19. | ALA4588661 | 16 | GI | 0 | ALA4380512 | Dose-dependent effect | ||||||
| 20. | ALA4588661 | 16 | GI | 0 | ALA4380511 | Dose-dependent effect |
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