# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4590082 | 7j | IC50 | > | 30 | uM | ALA4341378 | nM | Homo sapiens | |||
2. | ALA4590082 | 7j | Activity | 0 | ALA4341377 | Dose-dependent effect | Rattus norvegicus | |||||
3. | ALA4590082 | 7j | AUC | = | 6213 | hr.ng/ml | ALA4341376 | ng.hr.mL-1 | ||||
4. | ALA4590082 | 7j | AUC | = | 1488 | hr.ng/ml | ALA4341375 | ng.hr.mL-1 | ||||
5. | ALA4590082 | 7j | AUC | = | 330 | hr.ng/ml | ALA4341374 | ng.hr.mL-1 | ||||
6. | ALA4590082 | 7j | INH | = | 16.4 | % | ALA4341373 | % | Homo sapiens | |||
7. | ALA4590082 | 7j | INH | = | 11.2 | % | ALA4341372 | % | Homo sapiens | |||
8. | ALA4590082 | 7j | INH | = | 1.9 | % | ALA4341371 | % | Homo sapiens | |||
9. | ALA4590082 | 7j | Activity | 0 | ALA4341370 | Non-Toxic | ||||||
10. | ALA4590082 | 7j | Activity | 0 | ALA4341369 | Non-Toxic | ||||||
11. | ALA4590082 | 7j | Activity | = | 113.2 | % | ALA4341368 | % | Rattus norvegicus | |||
12. | ALA4590082 | 7j | Activity | = | 101.1 | % | ALA4341367 | % | Rattus norvegicus | |||
13. | ALA4590082 | 7j | Activity | = | 14.1 | % | ALA4341366 | % | Rattus norvegicus | |||
14. | ALA4590082 | 7j | F | = | 54.8 | % | ALA4341365 | % | ||||
15. | ALA4590082 | 7j | t1/2 | = | 2.91 | hr | ALA4341364 | hr | ||||
16. | ALA4590082 | 7j | MRT(t) | = | 3.49 | hr | ALA4341363 | hr | ||||
17. | ALA4590082 | 7j | CL | = | 4.31 | L/hr/kg | ALA4341345 | mL.min-1.kg-1 | ||||
18. | ALA4590082 | 7j | Vz | = | 17.82 | L/Kg | ALA4341362 | L.kg-1 | ||||
19. | ALA4590082 | 7j | AUCt | = | 2.19 | microg.hr/mL | ALA4341361 | ng.hr.mL-1 | ||||
20. | ALA4590082 | 7j | Cmax | = | 0.54 | ug ml-1 | ALA4341360 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM |