| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4590548 | 24 | ED50 | = | 2.9 | umol/Kg | ALA4329687 | umol.kg-1 | Canis lupus familiaris | |||
| 2. | ALA4590548 | 24 | ED50 | = | 7.6 | umol/Kg | ALA4329686 | umol.kg-1 | Rattus norvegicus | |||
| 3. | ALA4590548 | 24 | F | = | 52.6 | % | ALA4329683 | % | ||||
| 4. | ALA4590548 | 24 | t1/2 | = | 0.949 | min | ALA4329682 | hr | ||||
| 5. | ALA4590548 | 24 | Vdss | = | 1.54 | L/Kg | ALA4329681 | L.kg-1 | ||||
| 6. | ALA4590548 | 24 | CL | = | 23.6 | ml/min.kg | ALA4329680 | mL.min-1.kg-1 | ||||
| 7. | ALA4590548 | 24 | AUC | = | 753 | ng/mL.hr | ALA4329679 | ng.hr.mL-1 | ||||
| 8. | ALA4590548 | 24 | F | = | 97 | % | ALA4329672 | % | ||||
| 9. | ALA4590548 | 24 | t1/2 | = | 94.8 | min | ALA4329671 | hr | ||||
| 10. | ALA4590548 | 24 | Vdss | = | 2.8 | L/Kg | ALA4329670 | L.kg-1 | ||||
| 11. | ALA4590548 | 24 | CL | = | 35 | ml/min.kg | ALA4329669 | mL.min-1.kg-1 | ||||
| 12. | ALA4590548 | 24 | AUC | = | 904 | ng/mL.hr | ALA4329668 | ng.hr.mL-1 | ||||
| 13. | ALA4590548 | 24 | IC50 | = | 0.08 | uM | ALA4329667 | 7.10 | nM | Homo sapiens | ||
| 14. | ALA4590548 | 24 | permeability | = | 277 | nm/s | ALA4329666 | nm/s | ||||
| 15. | ALA4590548 | 24 | Kinetic_solubility | = | 130 | uM | ALA4329665 | nM | ||||
| 16. | ALA4590548 | 24 | pIC50 | = | 8 | ALA4329664 | 8.00 | nM | Homo sapiens |
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