# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4590913 | 6b; Table 1, Entry 10 | CLH | = | 9 | microL/min/mg | ALA4374639 | mL.min-1.g-1 | ||||
2. | ALA4590913 | 6b; Table 1, Entry 10 | Ratio | = | 2.7 | ALA4374638 | ||||||
3. | ALA4590913 | 6b; Table 1, Entry 10 | Papp | = | 4.2 | 10'-6 cm/s | ALA4374637 | 10'-6 cm/s | ||||
4. | ALA4590913 | 6b; Table 1, Entry 10 | Papp | = | 1.5 | 10'-6 cm/s | ALA4374636 | 10'-6 cm/s | ||||
5. | ALA4590913 | 6b; Table 1, Entry 10 | t1/2 | = | 88 | min | ALA4374635 | hr | ||||
6. | ALA4590913 | 6b; Table 1, Entry 10 | CLH | = | 16 | uL/min | ALA4374634 | uL/min | ||||
7. | ALA4590913 | 6b; Table 1, Entry 10 | t1/2 | > | 120 | min | ALA4374633 | hr | ||||
8. | ALA4590913 | 6b; Table 1, Entry 10 | EC50 | = | 13.5 | uM | ALA4374632 | 4.87 | nM | Homo sapiens |